NDLI: Comparison of 2D scintimammography and 3D dedicated breast SPECT using a compressible breast phantom and lesions of varying size and tracer uptake

Content Provider	IEEE Xplore Digital Library
Author	Cutler, Spencer J. Perez, Kristy L. Madhav, Priti Tornai, Martin P.
Copyright Year	2008
Description	Author affiliation: Biomedical Engineering and Radiology Departments, Duke University, Durham, NC 27710 USA (Cutler, Spencer J.; Madhav, Priti) \|\| Medical Physics Graduate Program and Radiology Department, Duke University, Durham, NC 27710 USA (Perez, Kristy L.) \|\| Medical Physics Graduate Program, Biomedical Engineering, and Radiology Departments, Duke University, Durham, NC 27710 USA (Tornai, Martin P.)
Abstract	This study aims to qualitatively and quantitatively compare 2D planar scintimammography imaging of the breast under various degrees of compression with uncompressed, dedicated 3D SPECT using dedicated acquisition trajectories. A 700mL compressible anthropomorphic breast phantom containing small lesions was developed to compare 2D and 3D breast imaging. Thin walled, deformable lesions ranging from 40 to 500uL volume suspended on a thin plastic sheet in the phantom were used to mimic breast lesions undergoing different degrees of compression. Using a $16×20cm^{2}$ CZT-based gamma camera, $^{99m}Tc-scintimammography$ was performed for 10min imaging times for compression thicknesses of 6 and 12cm (fully uncompressed) using a single mediolateral view. Dedicated breast SPECT was then performed for 10min using the uncompressed breast acquired with a simple tilted rotation, and a complex 3D acquisition trajectory. Experimental variables include: (1) background torso contamination; (2) (in)homogeneous breast composition; and (3) low count (clinically relevant) and high count (low noise) images. The radioactivity lesion:background concentration ratio was varied from 12:1 down to 3:1. A comparison between the two modalities was made in a limited observer study with independent observers evaluating reconstructed images for the smallest detectable lesion and total number of lesions. Image quality, based on lesion SNRs and contrasts were also evaluated. SPECT images appear to yield observation of smaller and more simulated lesions than those seen in scintimammography, additionally with more than twice the SNR and contrast. Due to greater positioning flexibility of the SPECT system gantry, under a wide range of measurement conditions, statistically significantly (p≪0.05) more lesions, smaller lesion sizes, and (3D) lesion locations were detected with dedicated breast SPECT than with compressed breast scintimammography.
Starting Page	5640
Ending Page	5646
File Size	10017054
Page Count	7
File Format	PDF
ISBN	9781424427147
ISSN	10957863
DOI	10.1109/NSSMIC.2008.4774523
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-10-19
Publisher Place	Germany
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Breast Imaging phantoms Lesions Optical imaging Anthropomorphism Thin wall structures Plastics Cameras Torso Contamination
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Comparison of scintimammography and dedicated emission mammotomography

Optimization of dedicated scintimammography procedure using detector prototypes and compressible phantoms

Towards patient imaging with dedicated emission mammotomography

SPECT breast imaging combining horizontal and vertical axes of rotation

Novel patient optimized acquisition trajectories for dedicated breast SPECT imaging

3D data acquisition sampling strategies for dedicated emission mammotomography for various breast sizes

Relative lesion detectability in 3D vs. 2D dedicated multi-ring PET

Breast tumor imaging using a tiltable head SPECT camera

Empirical effects of angular sampling and background content on image quality in dedicated breast SPECT

Comparison of 2D scintimammography and 3D dedicated breast SPECT using a compressible breast phantom and lesions of varying size and tracer uptake

Similar Documents

Comparison of scintimammography and dedicated emission mammotomography

Optimization of dedicated scintimammography procedure using detector prototypes and compressible phantoms

Towards patient imaging with dedicated emission mammotomography

SPECT breast imaging combining horizontal and vertical axes of rotation

Novel patient optimized acquisition trajectories for dedicated breast SPECT imaging

3D data acquisition sampling strategies for dedicated emission mammotomography for various breast sizes

Relative lesion detectability in 3D vs. 2D dedicated multi-ring PET

Breast tumor imaging using a tiltable head SPECT camera

Empirical effects of angular sampling and background content on image quality in dedicated breast SPECT

Comparison of 2D scintimammography and 3D dedicated breast SPECT using a compressible breast phantom and lesions of varying size and tracer uptake