NDLI: Active pixel sensors in Nuclear Medicine imaging

Content Provider	IEEE Xplore Digital Library
Author	Ott, Robert Evans, Noel Evans, Phil Osmond, John Clark, Andy Crooks, Jamie Prydderich, Mark Turchetta, Renato
Copyright Year	2008
Description	Author affiliation: Physics Department, Institute of Cancer Research/Royal Marsden Hospital, Sutton, Surrey, SM2, 5PT UK (Ott, Robert; Evans, Noel; Evans, Phil; Osmond, John) \|\| Rutherford Appleton Laboratories, STFC Centre for Instrumentation, Chilton, Oxon, UK (Clark, Andy; Crooks, Jamie; Prydderich, Mark; Turchetta, Renato)
Abstract	Three CMOS active pixel sensors have been investigated to assess their potential application to Nuclear Medicine imaging. The first, Startracker, contained 525 × 525 pixels each 25 micron square and was coupled via a fiber optic stud to a 20mm × 20mm × 2mm thick segmented CsI(Tl) crystal. Imaging tests were performed using $^{99m}Tc$ sources which emit 140 keV gamma rays together with various lead collimators. The system was interfaced to a PC via an FPGA-based DAQ and optical link enabling imaging rates of 10 frames per sec. System noise was measured to be ≫100e but the majority of this noise was found to be fixed pattern in nature. The intrinsic spatial resolution was measured as ∼80 microns and the system spatial resolution measured with a slit was ≪1mm. The second sensor, OPIC, had 64 × 72 pixels each 40 micron square and was used to evaluate noise characteristics of these sensors and to develop a method of differentiation between fixed pattern and statistical noise. The third sensor, Vanilla, had 520×520 pixels each 25micron square and a measured system noise of ∼25e. This sensor was coupled directly to the segmented phosphor. Results show that even at this lower level of noise the signal from 140 keV gamma rays is small as the light from the phosphor is spread over a large number of pixels. Suggestions for the ‘ideal’ sensor are made.
Starting Page	4883
Ending Page	4886
File Size	4252084
Page Count	4
File Format	PDF
ISBN	9781424427147
ISSN	10957863
DOI	10.1109/NSSMIC.2008.4774334
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-10-19
Publisher Place	Germany
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Pixel Image sensors Nuclear medicine Optical imaging Sensor phenomena and characterization CMOS image sensors Gamma rays Optical noise Noise measurement Spatial resolution
Content Type	Text
Resource Type	Article

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