NDLI: First test results of a commercially available clinical PET scanner using the NEMA NU 4

Content Provider	IEEE Xplore Digital Library
Author	Weidong Luo, Anashkin, Edward Matthews, Chris G.
Copyright Year	2008
Description	Author affiliation: Naviscan Inc., San Diego, CA 92121, USA (Weidong Luo,; Anashkin, Edward; Matthews, Chris G.)
Abstract	The recently published NEMA NU 4 - 2008 Standards has been specially designed for the performance evaluation of small animal PET scanners with appropriate scaling for the mice, rats or monkeys used in pre-clinical applications. In this paper, we report on the NU 4 performance of a commercially available clinical scanner (PEM Flex Solo II, Naviscan, Inc., San Diego) that was designed for human PET imaging of small organs such as the female breast. Due to the compact design of the PEM Flex, the NU 4 Standards is better suited for evaluating its performance over the clinical scanner standard of NU 2. The following results were obtained based on the NU 4 standard: Trans-axial spatial resolution 1.6 mm FWHM for high resolution reconstruction and 2.4 mm FWHM for standard resolution reconstruction with no significant variation within the field of view. The total system sensitivity was 0.16 cps/Bq. For the mouse and rat phantoms, the respective system sensitivities were 0.067 cps/Bq and 0.14 cps/Bq. In image quality testing, the uniformity was found to be 2.7% STD at the standard resolution mode and 6.1% at the high resolution mode. Although there is no specific NEMA testing protocol for planar geometry PET scanners, the NEMA NU 4 - 2008 Standards proved to be a useful tool to evaluate the performance of the PEM Flex scanner with minor modification to address the specifics of its detector configuration.
Starting Page	4718
Ending Page	4723
File Size	4225360
Page Count	6
File Format	PDF
ISBN	9781424427147
ISSN	10957863
DOI	10.1109/NSSMIC.2008.4774477
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-10-19
Publisher Place	Germany
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Positron emission tomography Testing Animals Spatial resolution Mice Image reconstruction Image resolution Standards publication Rats Humans
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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