NDLI: A high resolution PET insert system for clinical PET/CT scanners

Content Provider	IEEE Xplore Digital Library
Author	Heyu Wu, Tae Yong Song, Pal, Debashish Keesing, Daniel B. Komarov, Sergey O. Sullivan, Joseph A. Yuan-Chuan Tai,
Copyright Year	2008
Description	Author affiliation: BME, Washington University in St. Louis, MO 63105, USA (Pal, Debashish; Keesing, Daniel B.) \|\| ESE, Washington University in St. Louis, MO 63105, USA (O Sullivan, Joseph A.) \|\| Radiology Department (MIR), Washington University in St. Louis, MO 63110, USA (Heyu Wu,; Tae Yong Song,; Komarov, Sergey; Yuan-Chuan Tai,)
Abstract	We have developed a PET insert system that can be integrated into a clinical PET-CT scanner to improve its image resolution when imaging a patient for head and neck cancer. The system consists of 28 detector modules arranged into two half rings (24.6 cm in diameter). Each detector consists of an array of 13×13 LSO crystals each measuring 2 × 2 × 5 mm3, a 2.8 mm thick light-guide, and a R8900-M16 PMT (Hamamatsu, Japan). The 16 anode outputs of a PMT are multiplexed to produce 4 position-encoded signals that resemble the output of a typical block detector in the PET scanner. An active switch board was designed to select signals from either the insert detectors or scanner detectors and feed the output signals to system electronics for event processing, allowing the scanner to switch between its normal operation and the insert mode without shutting down the system. A 3-D translation stage supports and positions the insert concentrically inside the scanner. The axial extend of the insert detectors is 54 mm, centered within the first 3 detector block rings of the scanner. Initial setup of the PET insert system requires the identification of crystal lookup table and photopeak locations, timing alignment of the insert detectors with the scanner. Once completed, the scanner can be switched between the insert and normal modes within a few minutes. Coincidences are sorted into insert-insert (II), insert-scanner (IS) and scanner-scanner (SS) types of events using a custom sorting code. We have developed 2D FBP and 2D ML-EM algorithms to reconstruct single-slice rebinned sinograms, and a 3D OS-EM algorithm to jointly estimate the images using all 3 types of events. Initial tests show a mean, max and min energy resolution of 12.36%, 18.57% and 9.45% FWHM at 511 keV, respectively. Image resolution measured by 22Na point sources is ∼2–3 mm FWHM and improved from 4–5mm FWHM for scanner system. Full system performance is currently being evaluated.
Starting Page	5442
Ending Page	5444
File Size	6901266
Page Count	3
File Format	PDF
ISBN	9781424427147
ISSN	10957863
DOI	10.1109/NSSMIC.2008.4774485
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-10-19
Publisher Place	Germany
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Positron emission tomography Computed tomography Detectors Switches Image resolution Signal processing Event detection High-resolution imaging Head Neck
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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