NDLI: A new PET scanner for functional brain imaging based on 2-mm straw detectors

Content Provider	IEEE Xplore Digital Library
Author	Athanasiades, Athanasios Liang Sun, Martin, Christopher S. Lyons, Tom D. Nguyen, Richard V. Vazquez-Flores, Gerson J. Lacy, Jeffrey L.
Copyright Year	2008
Description	Author affiliation: Proportional Technologies, Inc., Houston, TX 77054, USA (Athanasiades, Athanasios; Liang Sun,; Martin, Christopher S.; Lyons, Tom D.; Nguyen, Richard V.; Vazquez-Flores, Gerson J.; Lacy, Jeffrey L.)
Abstract	Positron Emission Tomography (PET) is a uniquely valuable imaging modality for functional brain imaging that remains underutilized due to the lack of affordable, high-performance brain PET scanners. We propose a parallax-free, low-cost detector technology that offers high spatial resolution, high sensitivity, 3D position encoding, and simple readout without the use of photomultiplier tubes. The capabilities of the new detector are demonstrated in a new scanner design. The performance of the proposed scanner is explored in Monte Carlo simulations, implemented in MCNP5. The scanner consists of six detector heads arranged hexagonally, each containing thirty-five detector modules, and separated 22 cm from one another. Each module contains a 10×10 array of “straw” detectors, each 50 cm long, 2 mm in diameter and incorporating a thin layer of lead in their wall. Photons interacting in lead generate Compton- and photo-electrons that are subsequently counted in the gas contained within each straw detector. We predict that image resolution is close to 1 mm in all three directions (radial, tangential and axial), and remains uniform to within 15% over the entire transverse field of view (FOV). Sensitivity is 7.8%, for a point source in the center FOV, in the absence of a scattering medium. The transverse variation of sensitivity is on the order of 10%. The scatter fraction is 48% and the peak NECR is 165 kcps, obtained at 17.7 kBq/cc.
Starting Page	5445
Ending Page	5451
File Size	8497892
Page Count	7
File Format	PDF
ISBN	9781424427147
ISSN	10957863
DOI	10.1109/NSSMIC.2008.4774486
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-10-19
Publisher Place	Germany
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Positron emission tomography Brain Detectors High-resolution imaging Electromagnetic scattering Particle scattering Spatial resolution Encoding Photomultipliers Head
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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