NDLI: Parallel finite element reconstruction for spectrally-solved bioluminescence tomography

Content Provider	IEEE Xplore Digital Library
Author	Yujie Lu, Chatziioannou, Arion F.
Copyright Year	2008
Description	Author affiliation: Crump Institute for Molecular Imaging, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095 USA (Yujie Lu,; Chatziioannou, Arion F.)
Abstract	In Bioluminescence Tomography (BLT), a priori information is necessary to obtain unique BLT reconstruction. When using the explored a priori information, such as complex heterogeneous model and multispectral measurements, the reconstruction speed especially in whole-body small animal molecular imaging becomes slow. Because of the flexibility of the finite element method (FEM), reconstruction algorithms based on it are extensively developed. Fully 3D BLT reconstruction though is challenging. Although the computer hardware technology is rapidly developed, BLT reconstruction time becomes long, even impossible in a single PC when fine discretization is used to obtain the desirable spatial resolution. In this paper, a fully parallel 3D finite element reconstruction algorithm is proposed for spectrally-resolved BLT reconstruction. In this algorithm, anatomical information and multispectral measurements can be easily used to improve BLT reconstruction. Specifically, for parallelization, the reconstruction domain is partitioned into several subdomains corresponding to the number of nodes of the cluster. Establishment of a parallel linear relationship between the measured data and the unknown source distribution and optimization is performed to improve the reconstruction speed. In a numerical reconstruction, the effectiveness and potential is verified with a large-volume homogeneous phantom.
Starting Page	5414
Ending Page	5417
File Size	2089794
Page Count	4
File Format	PDF
ISBN	9781424427147
ISSN	10957863
DOI	10.1109/NSSMIC.2008.4774457
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-10-19
Publisher Place	Germany
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Finite element methods Bioluminescence Tomography Image reconstruction Velocity measurement Reconstruction algorithms Animals Molecular imaging Hardware Spatial resolution
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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