NDLI: Spatially variant positron range modeling derived from CT for PET image reconstruction

Content Provider	IEEE Xplore Digital Library
Author	Alessio, Adam MacDonald, Lawrence
Copyright Year	2008
Description	Author affiliation: Dept. of Radiology, University of Washington, Seattle, 98195 USA (Alessio, Adam; MacDonald, Lawrence)
Abstract	The influence of a finite positron annihilation distance represents a fundamental limit to the spatial resolution of PET scanners. It is appreciated that this effect is a minor concern in whole-body F18 imaging, but it does represent an issue when imaging with higher energy isotopes such as N13 or Rb82. This effect is especially relevant for imaging tasks along tissue gradients such as the cardiac/lung boundary and diaphragm/lung boundary. This work presents a method to determine the positron range effect from a CT scan and to model this effect as shift-variant, anisotropic kernels. The positron annihilation distance across boundaries of tissues is represented with a simple model, which can be quickly derived from CT scans and applied in the reconstruction of PET images. The positron range compensation map is applied in a modified OSEM algorithm to simulated and measured data.
Starting Page	3637
Ending Page	3640
File Size	5583533
Page Count	4
File Format	PDF
ISBN	9781424427147
ISSN	10957863
DOI	10.1109/NSSMIC.2008.4774106
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-10-19
Publisher Place	Germany
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Computed tomography Positron emission tomography Image reconstruction High-resolution imaging Whole-body PET Lungs Spatial resolution Isotopes Anisotropic magnetoresistance Kernel
Content Type	Text
Resource Type	Article

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