NDLI: The effect of energy on scintillation camera intrinsic spatial resolution

Content Provider	IEEE Xplore Digital Library
Author	Holstensson, M. Partridge, M. Buckley, S. E. Flux, G. D.
Copyright Year	2008
Description	Author affiliation: Joint Department of Physics, Institute of Cancer Research, Royal Marsden NHS Foundation Trust, Sutton, SM2 5PT, UK (Holstensson, M.; Partridge, M.; Flux, G. D.) \|\| Royal Marsden NHS Foundation Trust, SM2 5PT, Sutton, UK (Buckley, S. E.)
Abstract	Accurate activity quantification in Nuclear Medicine Imaging is a prerequisite for accurate absorbed dose calculations and quantitative biodistribution studies. Monte Carlo modelling is a useful tool for studying quantitative accuracy in scintillation camera imaging. In order to simulate spatial response, a value for the intrinsic spatial resolution is needed. In this study we have by means of experimental measurements and simulations investigated the intrinsic spatial resolution for the photopeaks of $^{99m}Tc,$ $^{111}In$ and $^{131}I.$ This was to enable the validation of the Monte Carlo code GATE. Experimental images were acquired on a 0.95 cm thick NaI(Tl) crystal Philips FORTE and a 1.59 cm thick NaI(Tl) crystal Philips SKYLight scintillation camera. A 1 mm slit phantom was placed in close proximity to the crystal and a source holder, constructed so that only a narrow beam of radiation was incident on the slit, was placed 1.5 m from the crystal. GATE was used to simulate projection data under the same conditions as the experiments. In the case of $^{111}In$ the two photopeaks (171.3 keV and 245.4 keV) were simulated separately. By comparing the known intrinsic spatial resolution of the crystal caused by multiple scattering of photons in the crystal to the total intrinsic spatial blurring, the intrinsic spatial component caused by electronic processing was estimated. Our data show that the intrinsic spatial blurring introduced by the electronics is dependent on the energy of the photons being imaged and can be accurately estimated. The difference between the intrinsic spatial resolution value for $^{99m}Tc$ (140.5 keV) and $^{131}I$ (364.5 keV) is 27% for the thin crystal and 21% for the thick crystal.
Starting Page	4811
Ending Page	4813
File Size	2727648
Page Count	3
File Format	PDF
ISBN	9781424427147
ISSN	10957863
DOI	10.1109/NSSMIC.2008.4774318
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-10-19
Publisher Place	Germany
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Cameras Spatial resolution Photonic crystals Monte Carlo methods Imaging phantoms Particle scattering Nuclear medicine Light scattering Nuclear and plasma sciences Medical simulation
Content Type	Text
Resource Type	Article

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