NDLI: Prediction of HLA-A*0201 Restricted Cytotoxic T Lymphocyte Epitopes in Influenza A H1N1 Virus and the Similarity Analysis of These Epitopes with Those Existing in Other Influenza Viruses

Content Provider	IEEE Xplore Digital Library
Author	Wang Fei-peng He Xian-hui
Copyright Year	2010
Abstract	In order to predict and compare the identities and differences of HLA-A0201 restricted cytotoxic T lymphocyte (CTL) epitopes among the influenza A virus ( H1N1), avian influenza virus (H5N1) and human influenza virus (H3N2). The SYFPEITHI, a T-cell epitope prediction tool, was adopted to predict the HLA-A0201-restricted CTL epitopes in the three influenza viruses; DNAMAN was used to analyze the sequence homology of the proteins contained in the three influenza viruses, which were retrieved from GenBank; The results revealed that a large number of CTL epitopes were shared by the H1N1, H5N1 and H3N2 viruses although significant divergence existed in the protein sequence. This in silico analysis demonstrated that the antigen cross-reaction existed in the three kinds of viruses, which may partly explain why many people who ever experienced H3N2 only displayed mild symptoms when infected with influenza A H1N1 virus. It also suggests that human influenza vaccine inoculation may help attenuate the course of H1N1 induced disease before influenza A H1N1 vaccine is available for the population.
Starting Page	1
Ending Page	4
File Size	242647
Page Count	4
File Format	PDF
ISBN	9781424447121
ISSN	21517622
DOI	10.1109/ICBBE.2010.5515558
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-06-18
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	In vivo Genetic mutations Influenza Humans Birds Vaccines Helium Viruses (medical) Immune system Diseases
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Identification of new HLA-A*0201-restricted cytotoxic T lymphocyte epitopes from neuritin

Prediction and identification of novel HLA-A*0201-restricted cytotoxic T lymphocyte epitopes from endocan

Simplex Virus Glycoprotein D Lymphocyte Epitopes Identified from Herpes Cytotoxic T + HLA-A * 0201-Restricted CD 8

LABORATORY INVESTIGATION Identification of new HLA-A*0201-restricted cytotoxic T lymphocyte epitopes from neuritin

Hla-restricted Virus-specific Cytotoxic T-lymphocyte Responses to Live and Inactivated Influenza Vaccines

Identification of human leucocyte antigen (HLA)-A*0201-restricted cytotoxic T lymphocyte epitopes derived from HLA-DOβ as a novel target for multiple myeloma

HLA-A*0201-Restricted CD8+ Cytotoxic T Lymphocyte Epitopes Identified from Herpes Simplex Virus Glycoprotein D

Communication identification of an hla-a*0201-restricted cytotoxic t-lymphocyte epitope in rotavirus (2006).

Identification and structural definition of H5-specific CTL epitopes restricted by HLA-A*0201 derived from the H5N1 subtype of influenza A viruses

Prediction of HLA-A*0201 Restricted Cytotoxic T Lymphocyte Epitopes in Influenza A H1N1 Virus and the Similarity Analysis of These Epitopes with Those Existing in Other Influenza Viruses

Similar Documents

Identification of new HLA-A*0201-restricted cytotoxic T lymphocyte epitopes from neuritin

Prediction and identification of novel HLA-A*0201-restricted cytotoxic T lymphocyte epitopes from endocan

Simplex Virus Glycoprotein D Lymphocyte Epitopes Identified from Herpes Cytotoxic T + HLA-A * 0201-Restricted CD 8

LABORATORY INVESTIGATION Identification of new HLA-A*0201-restricted cytotoxic T lymphocyte epitopes from neuritin

Hla-restricted Virus-specific Cytotoxic T-lymphocyte Responses to Live and Inactivated Influenza Vaccines

Identification of human leucocyte antigen (HLA)-A*0201-restricted cytotoxic T lymphocyte epitopes derived from HLA-DOβ as a novel target for multiple myeloma

HLA-A*0201-Restricted CD8+ Cytotoxic T Lymphocyte Epitopes Identified from Herpes Simplex Virus Glycoprotein D

Communication identification of an hla-a*0201-restricted cytotoxic t-lymphocyte epitope in rotavirus (2006).

Identification and structural definition of H5-specific CTL epitopes restricted by HLA-A*0201 derived from the H5N1 subtype of influenza A viruses

Prediction of HLA-A*0201 Restricted Cytotoxic T Lymphocyte Epitopes in Influenza A H1N1 Virus and the Similarity Analysis of These Epitopes with Those Existing in Other Influenza Viruses