NDLI: Investigation of 13 Kinds of Typical Environmental Endocrine Disruptors (EEDs) in Human Serum by Gas Chromatography-Mass Spectrometry-Selected Ion Monitoring (GC-MS-SIM)

Content Provider	IEEE Xplore Digital Library
Author	Chunying Liang Yongheng Chen Hongmei Deng
Copyright Year	2010
Abstract	13 kinds of typical Environmental Endocrine Disruptors (EEDs) in human serum were detected by Gas Chromatography-Mass Spectrometry-Selected ion Monitoring (GC-MS-SIM) simultaneously, and thirty copies of female serum samples (aged from 10 to 45) collected in Sichuan province, China were detected based on this method. GC-MS-SIM detection, internal standard method, TMCE+TMCS derivatization were used as qualitative and quantitative analysis methods to detect 13 kinds of typical EEDs in human serum simultaneously. The data showed that this method had good linear relation in the range of 10-1000 ng/ml for PAEs , 50-1000 ng/ml for BPA and 10-200 ng/ml for DES,E1,E2,EE2 and E3, and the correlation coefficients of standard curves were higher than 0.99. The percent relative standard deviations (%RSD) for detected congeners were 5%-14% in blind triplicate samples. The average recovery rate and relative standard deviation (RSD, n=3) of the 13 kinds of EEDs which be injected in the pre-extracted serum samples were 94.9% and 11.7%. Surrogate standard recoveries of DBP-d4 and BPA-d16 which were injected in all serum samples ranged from 67.98% to 110.8% and 60.12% to 102.35% (RSD＜14%). The results of 30 copies of actual serum samples showed that EEDs chemicals pollutants have entered the human body with a high content and posed a threat to human health. The people should attach great importance to that.
Starting Page	1
Ending Page	4
File Size	1096771
Page Count	4
File Format	PDF
ISBN	9781424447121
ISSN	21517622
DOI	10.1109/ICBBE.2010.5514770
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-06-18
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Fungi Spectroscopy Pollution Chemical analysis Plants (biology) Endocrine system Humans Aging Agriculture Monitoring
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
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7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
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9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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