NDLI: Multi-Objective Optimization Research for Effective Constituents of QiliQiangxin Capsule of Chinese Formula

Content Provider	IEEE Xplore Digital Library
Author	Hongtao Wang Jiming Jia Siwen Tang Dengfeng Xu Yajie Zheng Huixin Zhang Yiling Wu Renquan Liu
Copyright Year	2010
Abstract	The systematic effects from many active ingredients in Chinese medicine preparation are the highlight to evaluate curative effects and optimize the formula. The common design could get the ideal optimization. Qiliqiangxin(QLQX) capsule exerts its effects on chronic heart failure through cardiac and diuresis and dilating vessel. In our previous research 12 samples were obtained by water and alcohol extracting and macroporous resin purifying. The active sites were screened with the experiments of isolated frog heart and aorta perfusion and diuresis. The results suggested that W3,W4,E2,E3,E4 were major active sites. Here the LARS was adopted to design the experiment of heart failure in rats and optimize different index in the results. The study was to explore a novel method to optimize Chinese medicine formula.
Starting Page	1
Ending Page	3
File Size	261834
Page Count	3
File Format	PDF
ISBN	9781424447121
ISSN	21517622
DOI	10.1109/ICBBE.2010.5515683
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-06-18
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Heart Materials testing Biomedical materials Animals Cardiac disease Rats Medical tests Cardiovascular diseases Biological materials Design optimization
Content Type	Text
Resource Type	Article

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