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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Ahiskali, M. Green, D. Kounios, J. Clark, C.M. Polikar, R. |
| Copyright Year | 2009 |
| Description | Author affiliation: Dept. of Psychology, Drexel University, Philadelphia, PA ¿Contact author: Robi Polikar (Green, D.; Kounios, J.) || Signal Processing and Pattern Recognition Laboratory, Dept. of Electrical and Computer Eng. at Rowan University, Glassboro, NJ 08028, USA (Ahiskali, M.; Polikar, R.) || Department of Neurology, University of Pennsylvania, Philadelphia, PA (Clark, C.M.) |
| Abstract | As the average life expectancy increases, particularly in developing countries, prevalence of neurodegenerative diseases has also increased. This trend is especially alarming for Alzheimer's disease (AD); as there is no cure to stop or reverse the effects of AD. However, recent pharmacological advances can slow the progression of AD, but only if AD is diagnosed at early stages. We have previously introduced an ensemble of classifiers based approach for combining event related potentials obtained from different electrode locations as an effective approach for early diagnosis of AD. We further expand this approach and analyze its robustness and stability in two ways: comparing the diagnostic accuracy on hand selected and cleaned data vs. standard automated preprocessing, but more importantly, comparing the diagnostic accuracy on two different cohorts, whose data are collected under different settings: a research university lab and a community clinic. |
| Starting Page | 2494 |
| Ending Page | 2497 |
| File Size | 838458 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781424432967 |
| ISSN | 1557170X |
| DOI | 10.1109/IEMBS.2009.5335141 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2009-09-03 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Enterprise resource planning Proteins Biomedical signal processing Hospitals Alzheimer's disease Electrodes Robust stability Medical diagnostic imaging Biomarkers Electroencephalography |
| Content Type | Text |
| Resource Type | Article |
| Subject | Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition |
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