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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Suzuki, G. Leon, L.J. Kimber, S. Vigmond, E.J. |
| Copyright Year | 2009 |
| Description | Author affiliation: Electrical and Computer Engineering Department, University of Calgary, Calgary, Alberta T2N 1N4 Canada (Suzuki, G.; Vigmond, E.J.) || Faculty of Engineering, Dalhousie University, Halifax, B3H 4R2, Canada (Leon, L.J.) || Division of Cardiology, University of Alberta, Edmonton, AB, Canada T6G 2B 7 (Kimber, S.) |
| Abstract | Implantable cardioverter-defibrillaters (ICDs) are well known medical device for patients who are at a risk of sudden cardiac death caused by ventricular fibrillation (VF). The relationship between VF mechanisms and successful ICD therapy to terminate of VF is still not well understood. The purpose of this work is to evaluate the timing of ICD therapy as a predictor of successful VF termination. Clinical data sets were recorded from the patients who underwent ICD implantation in 6 Canadian centers. Timing of the defibrillation attempt (phase) was analyzed by using the ICD Marker Channel which monitors and displays cardiac events sensed by ICD. Phase, based on the VF period, was divided into 10 equally distributed bins and number of successful defibrillation episodes in each bin was compared. A total of 187 defibrillation attempts were identified from the 65 subjects. 126 of the defibrillation attempts were successful, while 61 failed. The optimal case was observed at a phase value of 1.2π with 2 successful attempts. The lowest performance rate was found at a phase value of 1.4π and 1.8π with 50% (3 and 2 successful attempts, respectively). The probability of success was analyzed by using generalized estimating equations (GEE) approach with an exchangeable correlation structure. The results of the GEE logistic regression model indicate no correlation between successful defibrillation attempts and phase of ventricular activity during VF (p-value = 3D 0.78). From our results, timing of defibrillation shock attempt is not a factor in successful termination of VF for patients undergoing ICD implantation. |
| Starting Page | 4759 |
| Ending Page | 4762 |
| File Size | 372594 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781424432967 |
| ISSN | 1557170X |
| DOI | 10.1109/IEMBS.2009.5334216 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2009-09-03 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Defibrillation Medical treatment Timing Electric shock Heart Cardiology Hospitals Programming profession Fibrillation Computer displays |
| Content Type | Text |
| Resource Type | Article |
| Subject | Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition |
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