NDLI: Evaluation of vibro-acoustography techniques to map absorbed dose distribution in irradiated phantoms

Content Provider	IEEE Xplore Digital Library
Author	Vieira, S.L. Kinnick, R.R. Baggio, A.L. Nicolucci, P. Fatemi, M. Carneiro, A.O.
Copyright Year	2009
Description	Author affiliation: Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA (Kinnick, R.R.; Fatemi, M.) \|\| Departamento de Física e Matemática, University of São Paulo, Riberão Preto, SP, Brazil (Vieira, S.L.; Baggio, A.L.; Nicolucci, P.; Carneiro, A.O.)
Abstract	This work presents Vibro-acoustography (VA) as a tool to visualize absorbed dose distributions in a polymer gel dosimeter. VA uses the radiation force of focused ultrasound to vibrate a small region of the sample. Different modalities of VA were used to investigate the feasibility of this technique to evaluate dose distribution in irradiated ‘MAGIC’ polymer gel. A phantom was designed using this polymer with 2% w/w added glass microspheres having an average diameter range between 40–75 µm. The phantom was irradiated using conventional 10 MeV X-rays from a linear accelerator at a distance of 100 cm. An absorbed dose of 50 gray was delivered to the gel. To study the phenomena of dose distribution, continuous wave (CW), toneburst and multifrequency VA were applied to the phantom. Images were generated from the phase and magnitude of the emitted sound from the irradiated area. The comparative accuracy of the different VA results were validated using transverse relaxation rate (R2) image analysis by Magnetic Resonance Imaging (MRI) and a treatment planning system. A contour map of R2 was registered with the transverse CW images, obtained with the focal point on the top surface, and a good correlation was found between the images. The axial profile of irradiated inclusion from the toneburst VA image obtained with excitation frequency of 75 kHz showed the best accuracy compared to other VA modalities. The results show that VA imaging has potential to visualize dose distribution in a polymer gel dosimeter.
Starting Page	796
Ending Page	799
File Size	524607
Page Count	4
File Format	PDF
ISBN	9781424432967
ISSN	1557170X
DOI	10.1109/IEMBS.2009.5333608
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-09-03
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Imaging phantoms Polymer gels Visualization Magnetic resonance imaging Focusing Ultrasonic imaging Glass X-rays Linear accelerators Image generation
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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