NDLI: Pulsed magneto-acoustic imaging

Content Provider	IEEE Xplore Digital Library
Author	Mehrmohammadi, M. Junghwan Oh Aglyamov, S.R. Karpiouk, A.B. Emelianov, S.Y.
Copyright Year	2009
Description	Author affiliation: Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 78712. He is now with the Department of Mechanical Engineering, Pukyong National University, South Korea (Junghwan Oh) \|\| Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 78712 USA (Mehrmohammadi, M.; Aglyamov, S.R.; Karpiouk, A.B.; Emelianov, S.Y.)
Abstract	Nanoparticles are attracting considerable interest as contrast agents for many different imaging modalities. Moreover, imaging the events at the cellular and molecular level is possible by using nanoparticles that have the desired targeting moiety. Unfortunately, ultrasound imaging cannot visualize the nano-structures directly due to its limited spatial resolution and contrast. We present a new technique, pulsed magneto-acoustic imaging, capable of imaging magnetic nanoparticles indirectly. In this method, a high-strength pulsed magnetic field is used to induce motion within the magnetically labeled tissue and ultrasound is used to detect internal tissue motion. Experiments on tissue-mimicking phantoms and ex-vivo animal tissues demonstrated a clear contrast between normal and iron-laden samples labeled with 5 nm magnetic nanoparticles. In addition, the sensitivity of this new imaging technique was investigated for different concentrations of magnetic agents. The results of the study suggest that magnetic nanoparticles can be used as contrast agents in pulsed magneto-acoustic imaging. Furthermore, PMA imaging could become an imaging tool capable of visualizing the cellular and molecular composition of deep-lying structures.
Starting Page	4771
Ending Page	4774
File Size	421841
Page Count	4
File Format	PDF
ISBN	9781424432967
ISSN	1557170X
DOI	10.1109/IEMBS.2009.5334214
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-09-03
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Ultrasonic imaging Magnetic flux Optical imaging Nanoparticles Magnetic fields High-resolution imaging Visualization Magnetic particles Spatial resolution Motion detection
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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