NDLI: Association between mechanics and structure in arteries and veins: Theoretical approach to vascular graft confection

Content Provider	IEEE Xplore Digital Library
Author	Salvucci, F.P. Bia, D. Armentano, R.L. Barra, J.G. Craiem, D. Zocalo, Y. Fernandez, J.D. Baguear, F. Atienza, J.M. Rojo, F.J. Guinea, G.V.
Copyright Year	2009
Description	Author affiliation: Physiology Department, School of Medicine, Republic University, Montevideo, Uruguay (Bia, D.; Zocalo, Y.; Fernandez, J.D.) \|\| Faculty of Engineering and Natural and Exact Sciences, Favaloro University, Buenos Aires, Argentina (Salvucci, F.P.; Armentano, R.L.; Barra, J.G.; Craiem, D.; Baguear, F.) \|\| Department of Materials Science, Technical University of Madrid, Spain (Atienza, J.M.; Rojo, F.J.; Guinea, G.V.)
Abstract	Biomechanical and functional properties of tissue engineered vascular grafts must be similar to those observed in native vessels. This supposes a complete mechanical and structural characterization of the blood vessels. To this end, static and dynamic mechanical tests performed in the sheep thoracic and abdominal aorta and the cava vein were contrasted with histological quantification of their main constituents: elastin, collagen and muscle cells. Our results demonstrate that in order to obtain adequate engineered vascular grafts, the absolute amount of collagen fibers, the collagen/elastin ratio, the amount of muscle cells and the muscle cells/elastic fibers ratio are necessary to be determined in order to ensure adequate elastic modulus capable of resisting high stretches, an adequate elastic modulus at low and normal stretch values, the correct viscous energy dissipation, and a good dissipation factor and buffering function, respectively.
Starting Page	4258
Ending Page	4261
File Size	359921
Page Count	4
File Format	PDF
ISBN	9781424432967
ISSN	1557170X
DOI	10.1109/IEMBS.2009.5334588
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-09-03
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Arteries Veins Muscles Blood vessels Mechanical factors Testing Biomedical imaging Abdomen Energy dissipation Viscosity
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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