NDLI: Image-based multiscale structural models of fibrous engineered tissues

Content Provider	IEEE Xplore Digital Library
Author	Sander, E.A. Tranquillo, R.T. Barocas, V.H.
Copyright Year	2009
Description	Author affiliation: University of Minnesota, Minneapolis, MN, USA (Sander, E.A.; Tranquillo, R.T.; Barocas, V.H.)
Abstract	While it is firmly established that the mechanical behavior of most biological tissues, including bioengineered tissues, is governed by an underlying network of protein fibers, it is still not clear how best to obtain and utilize structural information to predict mechanical response. In this paper, methods are presented to (1) quantify the fiber arrangement in a tissue from different imaging tools, (2) incorporate that structure into a multiscale model, and (3) solve the model equations to predict both the microscopic and the macroscopic tissue response. In principle these concepts could be applied to any tissue (incorporating the specific tissue components as needed), but for demonstration purposes, the focus of the current work is on cell-compacted collagen gel, a model engineered tissue.
Starting Page	4270
Ending Page	4272
File Size	786149
Page Count	3
File Format	PDF
ISBN	9781424432967
ISSN	1557170X
DOI	10.1109/IEMBS.2009.5334586
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-09-03
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Optical fiber polarization Optical fiber theory Biological tissues Predictive models Scanning electron microscopy Optical imaging Equations USA Councils Biological system modeling Protein engineering
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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