NDLI: Age-related changes in reservoir and excess components of central aortic pressure in asymptomatic adults

Content Provider	IEEE Xplore Digital Library
Author	Bia, D. Cymberknop, L. Zocalo, Y. Farro, I. Torrado, J. Farro, F. Pessana, F. Armentano, R.L.
Copyright Year	2011
Description	Author affiliation: Physiology Department, School of Medicine, Centro Universitario de Investigación, Innovación y Diagnóstico Arterial (CUiiDARTE), Republic University. General Flores 2125, Montevideo, Uruguay (Bia, D.; Zocalo, Y.; Farro, I.; Torrado, J.; Farro, F.; Armentano, R.L.) \|\| Electronic Department, Buenos Aires Regional Faculty, National Technological University, Medrano 951, (C1179AAQ), Buenos Aires, Argentina (Cymberknop, L.; Pessana, F.)
Abstract	Study of humans aging has presented difficulties in separating the aging process from concomitant disease and/or in defining normality and abnormality during its development. In accordance with this, aging associates structural and functional changes evidenced in variations in vascular parameters witch suffer alterations during atherosclerosis and have been proposed as early markers of the disease. The absence of adequate tools to differentiate the expected (normal) vascular changes due to aging from those related with a vascular disease is not a minor issue. For an individual, an early diagnosis of a vascular disease should be as important as the diagnosis of a healthy vascular aging. Recent studies have proposed that the capacitive or reservoir function of the aorta and large elastic arteries plays a major role in determining the pulse wave morphology. The arterial pressure waveform can be explained in terms of a reservoir pressure, related to the arterial system compliance, and an “excess” or wave-related pressure, associated with the traveling waves. The aim of this study was to evaluate, by means of a mathematical approach, age-related changes in measured, reservoir and excess central aortic pressure in order to determine if age-related changes are concentrated in particular decades of life. Central aortic pressure waveform was non-invasively obtained in healthy subjects (age range: 20–69 years old). Age-related profiles in measured, reservoir and excess pressure were calculated.
Starting Page	6454
Ending Page	6457
File Size	634498
Page Count	4
File Format	PDF
ISBN	9781424441211
ISSN	1557170X
e-ISBN	9781457715891
e-ISBN	9781424441228
DOI	10.1109/IEMBS.2011.6091593
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-08-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Reservoirs Aging Pressure measurement Arteries Diseases Blood pressure Humans
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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