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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Moorman, J.R. Rusin, C.E. Hoshik Lee Guin, L.E. Clark, M.T. Delos, J.B. Kattwinkel, J. Lake, D.E. |
| Copyright Year | 2011 |
| Description | Author affiliation: Department of Physics, College of William and Mary (Hoshik Lee; Delos, J.B.) || Departments of Medicine and Pediatrics, University of Virginia (Rusin, C.E.; Guin, L.E.; Clark, M.T.; Kattwinkel, J.; Lake, D.E.) || Department of Internal Medicine, University of Virginia; (Box 800158, Charlottesville, VA, USA (Moorman, J.R.) |
| Abstract | We wish to save lives of patients admitted to ICUs. Their mortality is high enough based simply on the severity of the original injury or illness, but is further raised by events during their stay. We target those events that are subacute but potentially catastrophic, such as infection. Sepsis, for example, is a bacterial infection of the bloodstream, that is common in ICU patients and has a >25% risk of death. Logically, early detection and treatment with antibiotics should improve outcomes. Our fundamental precepts are (1) some potentially catastrophic medical and surgical illnesses have subclinical phases during which early diagnosis and treatment might have life-saving effects, (2) these phases are characterized by changes in the normal highly complex but highly adaptive regulation and interaction of the nervous system and other organs such as the heart and lungs, (3) teams of clinicians and quantitative scientists can work together to identify clinically important abnormalities of monitoring data, to develop algorithms that match the clinicians' eye in detecting abnormalities, and to undertake the clinical trials to test their impact on outcomes. |
| Starting Page | 5515 |
| Ending Page | 5518 |
| File Size | 1636518 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781424441211 |
| ISSN | 1557170X |
| e-ISBN | 9781457715891 |
| e-ISBN | 9781424441228 |
| DOI | 10.1109/IEMBS.2011.6091407 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2011-08-30 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Pediatrics Monitoring Biomedical monitoring Heart rate variability Lakes Databases |
| Content Type | Text |
| Resource Type | Article |
| Subject | Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition |
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