NDLI: Biological and physical methods for risk estimation in interventional radiology: A detrimental effect approach

Content Provider	IEEE Xplore Digital Library
Author	Ramos, M. Montoro, A. Almonacid, M. Barquinero, S. Ferrer J. F. Tortosa, R. Miro, R. Verdu, G. Rodriguez, P. Barrios, L. L. Villaescusa, J. I.
Copyright Year	2011
Description	Author affiliation: Departament of Physiology and Cellular Biology. Unit of Cellular Biology (UAB) (Rodriguez, P.; Barrios, L L) \|\| Biological Dosimetry Service. Unit of Antrophol-ogy, Department of Animal and Vegetable Biology and Ecology. Universitat Autonoma de Barcelona (UAB) (Barquinero, S Ferrer J F) \|\| Radiation Protection Service of the Hospital La Fe of Valencia (Spain) (Montoro, A; Almonacid, M; Tortosa, R; Villaescusa, J I) \|\| Department of Chemical and Nuclear Engineering, Polytechnic University of Valencia, Camino de Vera s/n 46022 Valencia (Spain) (Ramos, M; Miro, R; Verdu, G)
Abstract	Interventional radiologists and staff members are frequently exposed to the effects of direct and scattered radiation, which undergo in deterministic effects (radiodermitis, aged skin, cataracts, telangiectasia in nasal region, vasocellular epitelioms, hands depilation) and/or stochastic ones (cancer incidence). A methodology has been proposed for estimating the radiation risk or detriment from a group of six exposed interventional radiologists of the Hospital Universitario La Fe (Valencia, Spain), which had developed general exposition symptoms attributable to deterministic effects of ionizing radiation. Equivalent doses have been periodically registered using termoluminiscence dosimeters (TLD's) and wrist dosimeters, Hp(10) and Hp(0.07), respectively, and estimated through the observation of translocations in lymphocytes of peripheral blood (biological methods), by extrapolating the yield of translocations to their respective dose-effect curves. The software RADRISK has been applied for estimating radiation risks in these occupational radiation exposures. The minimum and maximum average excess ratio for skin cancer has been, using wrist physical doses, of [1.03 × $10^{−3},$ 5.06 × $10^{−2}],$ concluding that there is not an increased risk of skin cancer incidence. The minimum and maximum average excess ratio for leukemia has been, using TLD physical doses, of [7.84 × $10^{−2},$ 3.36 × $10^{−1}],$ and using biological doses, of [1.40 × $10^{−1},$ 1.51], which is considerably higher than incidence rates, showing an excess radio-induced risk of leukemia in the group under study. Finally, the maximum radiological detriment in the group, evaluated as the total number of radio-induced cancers using physical dosimetry, has been of 2.18 per 1000 person-year (skin and leukemia), and using biological dosimetry of 9.20 per 1000 PY (leukemia). As a conclusion, this study has provided an assessment of the non-deterministic effects (rate of radio-induced cancer incidence) attributable to the group under study due to their professional activity.
Starting Page	108
Ending Page	111
File Size	371018
Page Count	4
File Format	PDF
ISBN	9781424441211
ISSN	1557170X
e-ISBN	9781457715891
e-ISBN	9781424441228
DOI	10.1109/IEMBS.2011.6089908
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-08-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Dosimetry Wrist Ionizing radiation Skin cancer Skin radiation protection Interventional radiology radiation risk biological dosimetry
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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