NDLI: Next generation brain implant coatings and nerve regeneration via novel conductive nanocomposite development

Content Provider	IEEE Xplore Digital Library
Author	Antoniadou, E.V. Ahmad, R.K. Jackman, R.B. Seifalian, A.M.
Copyright Year	2011
Description	Author affiliation: London Center for Nanotechnology and Department of Electronic and Electrical Engineering /UCL-Imperial College, London, United Kingdom (Ahmad, R.K.; Jackman, R.B.) \|\| Centre for Nanotechnology and Regenerative Medicine, Division of Surgery and Interv. Sciences, Royal Free Hospital, Medical School, UCL (Antoniadou, E.V.; Seifalian, A.M.)
Abstract	Composite materials based on the coupling of conductive organic polymers and carbon nanotubes have shown that they possess properties of the individual components with a synergistic effect. Multi-wall carbon nanotube (MWCNT)/ polymer composites are hybrid materials that combine numerous mechanical, electrical and chemical properties and thus, constitute ideal biomaterials for a wide range of regenerative medicine applications. Although, complete dispersion of CNT in a polymer matrix has rarely been achieved, in this study we have succeeded high dispersibility of CNT in POSS-PCU and POSS-PCL, novel polymers based on polyprolactone and polycarbonate polyurethane (PCU) and poly(caprolactoneurea)urethane both having incorporated polyhedral oligomeric silsesquioxane (POSS). We report the synthesis and characterization of a novel biomaterial that possesses unique properties of being electrically conducting and thus being capable of electronic interfacing with tissue. To this end, POSS-PCU/MWCNT composite can be used as a biomaterial for the development of nerve guidance channels to promote nerve regeneration and POSS-PCL/MWCNT as a substrate to increase electronic interfacing between neurons and micro-machined electrodes for potential applications in neural probes, prosthetic devices and brain implants.
Starting Page	3253
Ending Page	3257
File Size	1611970
Page Count	5
File Format	PDF
ISBN	9781424441211
ISSN	1557170X
e-ISBN	9781457715891
e-ISBN	9781424441228
DOI	10.1109/IEMBS.2011.6090884
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-08-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Plastics Carbon nanotubes Conductivity Coatings Chemicals Impedance coated brain microelectrodes carbon nanotubes nanomaterials
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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