NDLI: Distilling clinically interpretable information from data collected on next-generation wearable sensors

Content Provider	IEEE Xplore Digital Library
Author	Haslam, B. Gordhandas, A. Ricciardi, C. Verghese, G. Heldt, T.
Copyright Year	2011
Description	Author affiliation: Clinical Research Center, Massachusetts Institute of Technology, Cambridge MA, USA (Haslam, B.; Ricciardi, C.) \|\| Computational Physiology and Clinical Inference Group, Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge MA, USA (Gordhandas, A.; Verghese, G.; Heldt, T.)
Abstract	Medical electronic systems are generating ever larger data sets from a variety of sensors and devices. Such systems are also being packaged in wearable designs for easy and broad use. The large volume of data and the constraints of low-power, extended-duration, and wireless monitoring impose the need for on-chip processing to distill clinically relevant information from the raw data. The higher-level information, rather than the raw data, is what needs to be transmitted. We present one example of information processing for continuous, high-sampling-rate data collected from wearable and portable devices. A wearable cardiac and motion monitor designed by colleagues at MIT simultaneously records electrocardiogram (ECG) and 3-axis acceleration to onboard memory, in an ambulatory setting. The acceleration data is used to generate a continuous estimate of physical activity. Additionally, we use a Portapres continuous blood pressure monitor to concurrently record the arterial blood pressure (ABP) waveform. To help reduce noise, which is an increased challenge in ambulatory monitoring, we use both the ECG and ABP waveforms to generate a robust measure of heart rate from noisy data. We also generate an overall signal abnormality index to aid in the interpretation of the results. Two important cardiovascular quantities, namely cardiac output (CO) and total peripheral resistance (TPR), are then derived from this data over a sequence of physical activities. CO and TPR can be estimated (to within a scale factor) from heart rate, pulse pressure and mean arterial blood pressure, which in turn are directly obtained from the ECG and ABP signals. Data was collected on 10 healthy subjects. The derived quantities vary in a manner that is consistent with known physiology. Further work remains to correlate these values with the cardiac health state.
Starting Page	1729
Ending Page	1732
File Size	1395756
Page Count	4
File Format	PDF
ISBN	9781424441211
ISSN	1557170X
e-ISBN	9781457715891
e-ISBN	9781424441228
DOI	10.1109/IEMBS.2011.6090495
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-08-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Biomedical monitoring Heart rate Electrocardiography Monitoring Noise Wearable sensors
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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