NDLI: Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats

Content Provider	IEEE Xplore Digital Library
Author	Kawada, Toru Shimizu, Shuji Sata, Yusuke Kamiya, Atsunori Sunagawa, Kenji Sugimachi, Masaru
Copyright Year	2011
Description	Author affiliation: Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan (Sunagawa, Kenji) \|\| Department of Cardiovascular Dynamics, National Cerebral and Cardiovascular Center, 565-8565 Osaka, Japan (Kawada, Toru; Shimizu, Shuji; Sata, Yusuke; Kamiya, Atsunori; Sugimachi, Masaru)
Abstract	The carotid sinus baroreflex is one of the most important negative feedback systems to stabilize arterial pressure. Although static characteristics of the carotid sinus baroreflex can be assessed by using a stepwise input protocol under baroreflex open-loop conditions, the step duration has been determined empirically. In the present study, we examined the effects of different time windows (5–10, 15–20, 25–30, 35–40, 45–50, and 55–60 s) on the static characteristics estimated by using a 60-s stepwise input protocol in 10 anesthetized rats. Based on the results, we compared the static characteristics between actual 60-s and 20-s stepwise input protocols. Most of the parameters of the static characteristics did not differ significantly between the 60-s and 20-s stepwise input protocols, suggesting that the open-loop baroreflex static characteristics can be estimated by using a stepwise input with the step duration as short as 20 s in normal rats.
Starting Page	689
Ending Page	692
File Size	1726137
Page Count	4
File Format	PDF
ISBN	9781424441211
ISSN	1557170X
e-ISBN	9781457715891
e-ISBN	9781424441228
DOI	10.1109/IEMBS.2011.6090155
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-08-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Protocols Baroreflex Heart rate Rats Carotid arteries Steady-state
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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