NDLI: Noninvasive method for measuring respiratory system compliance during pressure support ventilation

Content Provider	IEEE Xplore Digital Library
Author	Zhanqi Zhao Eger, M. Handzsuj, T. Ranieri, V.M. Appendini, L. Micelli, C. Moller, K.
Copyright Year	2011
Description	Author affiliation: Department of Anesthesia and Intensive Care Medicine, University of Turin - S. Giovanni Battista Molinette Hospital, Turin, Italy (Ranieri, V.M.) \|\| Dräger Medical, Lübeck, Germany (Eger, M.; Handzsuj, T.) \|\| Department of Pneumology, Fondazione S. Maugeri, IRCCS, Istituto Scientifico di Veruno, Veruno, Italy (Appendini, L.) \|\| KleisTEK, Monopoli, Italy (Micelli, C.) \|\| Department of Biomedical Engineering, Furtwangen University, D-78054, VS-Schwenningen, Germany (Zhanqi Zhao; Moller, K.)
Abstract	Purpose: To date, few methods have been accepted for assessing the respiratory system compliance (Crs) in patients under assisted ventilation at the bedside. The aim of this study was to evaluate our adaptive time slice method (ATSM) to continuously calculate the Crs. Methods: One breath is divided into several time periods (slices). For each slice, a compliance value Ci is calculated. The slice width is adapted according to the confidence interval of Ci. After all Ci values are obtained and the outliers are eliminated, the Crs of this breath is calculated as the mean value of the remainder of Ci's. Seven patients with Chronic Obstructive Pulmonary Disease were evaluated during pressure support ventilation. The results are compared with the values calculated with the transdiaphragmatic pressure (Pdi). Results: 95±4% of the recorded data could be analyzed with ATSM. In 6 patients out of 7, the results delivered with ATSM and with Pdi had similar variation (standard deviation) and accuracy (difference<20%). They were strongly correlated (weighted correlation coefficient = 0.86, $p<10^{−5})$ with a mean difference of 3.22 ml/mbar. Conclusions: The ATSM is a robust method and able to provide accurate Crs in spontaneously breathing patients during pressure support ventilation noninvasively without extra instrumentation or complicated maneuvers.
Starting Page	3808
Ending Page	3811
File Size	489294
Page Count	4
File Format	PDF
ISBN	9781424441211
ISSN	1557170X
e-ISBN	9781457715891
e-ISBN	9781424441228
DOI	10.1109/IEMBS.2011.6090772
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-08-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Ventilation Muscles Phasor measurement units Lungs Resistance Correlation chronic obstructive pulmonary disease respiratory system compliance transdiaphragmatic pressure pressure support ventilation
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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