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Content Provider | IEEE Xplore Digital Library |
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Author | Armentano, Ricardo L. Bia, Daniel Zocalo, Yanina Torrado, Juan Farro, Ignacio Farro, Federico Florio, Lucia Olascoaga, Alicia Alallon, Walter Negreira, Carlos Lluberas, Ricardo |
Copyright Year | 2011 |
Description | Author affiliation: Physiology Department, School of Medicine, Centro Universitario de Investigación, Innovación y Diagnóstico Arterial (CUiiDARTE), Republic University. General Flores 2125, Montevideo, Uruguay. PC: 11800 (Armentano, Ricardo L.; Bia, Daniel; Zocalo, Yanina; Torrado, Juan; Farro, Ignacio; Farro, Federico) || Clinical Laboratory Department, School of Medicine, Republic University. Montevideo, Uruguay (Olascoaga, Alicia; Alallon, Walter) || Cardiology Department, School of Medicine, CUiiDARTE, Republic University, Montevideo, Uruguay (Florio, Lucia; Lluberas, Ricardo) || Physics Institute, School of Science, CUiiDARTE, Republic University. Montevideo, Uruguay (Negreira, Carlos) |
Abstract | In this work we present an initiative to develop a national (Uruguayan) program to evaluate vascular age and to detect pre-clinical atherosclerosis using: gold-standard technologies; complimentary and integrative approaches to asses arterial functional and structural indexes; data bases systems to process, analyze and determine normal and reference values and to identify the most sensitive markers of vascular changes for different ages. We evaluated, in a Uruguayan population complementary structural and functional vascular parameters that associate aging-related changes and are considered markers of sub-clinical atherosclerosis. Traditional CV risk factors were assessed. The subjects (n=281) were submitted to non-invasive vascular studies to evaluate: 1) Common carotid artery (CCA) intima-media thickness and diameter waveforms, 2) CCA stiffness, 3) aortic stiffness (pulse wave velocity) and 4) peripheral and central pressure pulse wave derived parameters. Age groups: 21–30, 31–40, 41–50, 51–60, and 61–70 years-old. Age-related profiles were obtained for the different vascular parameters, and their utility to assess vascular changes in young, middle-aged and old subjects was evaluated. The work has the strength of being the first that uses, in Latin-America an integrative approach to characterize vascular aging-related changes. |
Starting Page | 842 |
Ending Page | 845 |
File Size | 556928 |
Page Count | 4 |
File Format | |
ISBN | 9781424441211 |
ISSN | 1557170X |
e-ISBN | 9781457715891 |
e-ISBN | 9781424441228 |
DOI | 10.1109/IEMBS.2011.6090192 |
Language | English |
Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Publisher Date | 2011-08-30 |
Publisher Place | USA |
Access Restriction | Subscribed |
Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Subject Keyword | Indexes Aging Atherosclerosis Educational institutions Diseases Arteries Laboratories |
Content Type | Text |
Resource Type | Article |
Subject | Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition |
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