| Content Provider |
World Health Organization (WHO)-Global Index Medicus |
| Author |
Lu, Y. Y. Fu, H. J. Chen, X. L. Xu, X. Liu, S. S. Cai, Y. Y. Zhuang, Q. J. Zhang, Y. Zhu, M. Y. Li, F. Zhu, Y. X. Shen, C. Y. Xu, G. Li, S. H. Jiang, Y. Q. |
| Spatial Coverage |
China |
| Description |
Country affiliation: China Author Affiliation: Jiang YQ ( Shanghai Municipal First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China.); Zhu YX ( Songjiang Branch of Shanghai Municipal First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China.); Chen XL ( Songjiang Branch of Shanghai Municipal First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China.); Xu X ( Songjiang Branch of Shanghai Municipal First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China.); Li F ( Songjiang Branch of Shanghai Municipal First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China.); Fu HJ ( Xiaokunshan Town Primary Care of Songjiang District, Shanghai, China.); Shen CY ( Xiaokunshan Town Primary Care of Songjiang District, Shanghai, China.); Lu YY ( Xiaokunshan Town Primary Care of Songjiang District, Shanghai, China.); Zhuang QJ ( Xinbang Town Primary Care of Songjiang District, Shanghai, China.); Xu G ( School of Public Health, Shanghai Jiao Tong University, Shanghai, China.); Cai YY ( Institute of Respiratory Disease, Zhongshan Hospital Affiliated to Fudan University, Shanghai, China.); Zhang Y ( Shanghai Songjiang District Public Health Bureau, Shanghai, China.); Liu SS ( Shanghai Songjiang District Center for Diseases Control and Prevention, Shanghai, China.); Zhu MY ( Shanghai Songjiang District Center for Diseases Control and Prevention, Shanghai, China.); Li SH ( Songjiang Branch of Shanghai Municipal First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China.) |
| Abstract |
We performed a 1-year cluster-randomized field trial to assess the effect of standardized management of chronic obstructive pulmonary disease (COPD) on lung function and quality of life (QOL) measures in patients in China. We used the Global Initiative for Chronic Obstructive Lung Disease (GOLD) treatment guidelines and assessed indexes including pulmonary function, QOL, quality-adjusted life years (QALY), Medical Research Council (MRC) dyspnea scale, 6-min walk distance (6-MWD), number of emergency visits, and frequency of hospitalization. Of a total of 711 patients with chronic cough and asthma, 132 were diagnosed as having COPD and 102 participated in this study [intervention group (N = 47); control group (N = 55)]. We found that adherence to GOLD guidelines had a perceivable impact on 6-MWD, MRC dyspnea scale score, and QOL. The average QALY increased by 1.42/person/year in the intervention group, but declined by 0.95/person/year in the control group. We conclude that standardized management improves disease severity, QOL, and QALY in COPD patients when treatment protocols adhere to GOLD guidelines. |
| e-ISSN |
16765680 |
| Journal |
Genetics and Molecular Research |
| Issue Number |
3 |
| Volume Number |
14 |
| Language |
English |
| Publisher |
Fundação de Pesquisas Científicas de Ribeirão Preto |
| Publisher Date |
2015-08-03 |
| Publisher Place |
Brazil |
| Access Restriction |
Open |
| Subject Keyword |
Pulmonary Disease, Chronic Obstructive Diagnosis Therapy Walking Physiology Case-control Studies Cost-benefit Analysis Dyspnea Physiopathology Guideline Adherence Patient Compliance Prevention & Control Quality Of Life Quality-adjusted Life Years Respiratory Function Tests Randomized Controlled Trial Research Support, Non-u.s. Gov't Discipline Genetics Discipline Molecular Biology Discipline Bioinformatics |
| Content Type |
Text |
| Resource Type |
Article |
