NDLI: MR compatible brain PET using tileable GAPD arrays

Content Provider	IEEE Xplore Digital Library
Author	Jin Ho Jung Yong Choi Key Jo Hong Ji Hoon Kang Wei Hu Byung Jun Min Yoon Suk Huh Seung Han Shin Hyun Keong Lim Dae Shik Kim Han Byul Jin
Copyright Year	2009
Description	Author affiliation: Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 135-710, Korea (Jin Ho Jung; Yong Choi; Key Jo Hong; Ji Hoon Kang; Wei Hu; Byung Jun Min; Yoon Suk Huh; Seung Han Shin; Hyun Keong Lim; Dae Shik Kim; Han Byul Jin)
Abstract	The aim of this study is to develop a MR compatible PET that is insertable to MRI and allows simultaneous PET and MR imaging of human brain. The brain PET having 72 detector modules arranged in a ring of 330 mm diameter was designed. Each PET module composed of 4 × 4 matrix of 3 mm × 3 mm × 20 mm LYSO crystals coupled to a tileable 4 × 4 array Geigermode avalanche photodiode (GAPD) and designed to locate between RF and gradient coils. Signals of the each module were transferred to preamplifiers using flexible flat cable of 3 m long, and then sent to a position decoder circuit (PDC), which outputs digital address and an analog pulse of the one interacted channel from preamplifier signals. The PDC outputs were fed into FPGA-embedded DAQ boards. The analog signal was digitized, and arrival time and energy of the signal were calculated and stored. All electronics were located outside MR bore to minimize signal interference between PET and MR. Basic performance of the PET components and cross-compatibilities of the PET module and MR were evaluated. Imaging performance of the designed brain PET was investigated using Monte Carlo simulation and experimental measurement. The degradation of PET performance caused by the 3 m long cable and the PDC was negligibly small. No obvious differences of the PET module performance measured inside/outside MR bore were observed. The SNR of various MR sequence phantom images acquired with/without the PET module were also similar. Activity distribution patterns of hot-rod phantoms were well imaged without distortion, and rods down to a diameter of 3.5 mm were resolved in both simulation and experiment. Gray and white matter of the Hoffman brain phantom was also well imaged. Preliminary experimental results demonstrate that MR compatible high quality PET imaging is feasible using the GAPD arrays, electronics, signal processing method and MR insertable PET design schemes developed in this study.
Starting Page	3556
Ending Page	3559
File Size	530325
Page Count	4
File Format	PDF
ISBN	9781424439614
ISSN	10957863
DOI	10.1109/NSSMIC.2009.5401815
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-10-24
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Positron emission tomography Imaging phantoms Preamplifiers Power cables Boring Magnetic resonance imaging Humans Detectors Crystals Coupling circuits
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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