NDLI: Performance evaluation of GAPD-based brain PET

Content Provider	IEEE Xplore Digital Library
Author	Jiwoong Jung Yong Choi Jin Ho Jung Sangsu Kim Ki Chun Im Hyeok-jun Choe
Copyright Year	2013
Description	Author affiliation: Dept. of Electron. Eng., Sogang Univ., Seoul, South Korea (Jiwoong Jung; Yong Choi; Jin Ho Jung; Sangsu Kim; Ki Chun Im; Hyeok-jun Choe)
Abstract	A Geiger-mode avalanche photodiode (GAPD) is actively studied silicon-based photo-detector that is a promising photo-sensor for PET because of various advantages, such as gain, compact size, fast response and magnetic field insensitivity. Previously, we have developed a brain PET employing GAPD-based PET detector block, charge signal transmission method via 4 m long cable, high density position decoder circuit (PDC) and digital signal processing with FPGA-embedded ADC boards. The purpose of this study was to evaluate the performance of the developed brain PET system. The PET consists of 18 detector blocks, each of which comprises 4 × 4 GAPDs and 4 × 4 LYSO arrays. The output signals of PET detector block were amplified by preamplifier circuits and then transferred to the PDC. The PDC was used to identify the one valid channel among 256 channels of PET detector blocks and to output digital address analog pulse corresponding to the valid channel. Three FPGA-embedded DAQ boards were used to digitize analog output signals of the PDCs. The gain uniformity, spatial resolution, sensitivity, stability and count rate performance were measured. Tomographic image of 3D Hoffman brain phantom was also acquired to evaluate imaging capability of the PET. Normalized average photo-peak positions of PET detector block were 1.0 ± 0.14 without the gain correction and 1.0 ± 0.03 with the gain correction. Spatial resolution and sensitivity in the center of field of view were 3.1 mm and 0.8%, respectively. The average scatter fraction was 0.4 with lower energy threshold of 350 keV. The maximum true count rate and maximum NECR were measured 43.3 kcps and 6.5 kcps at an activity concentration of 16.7 kBq/ml and 5.5 kBq/ml, respectively. Activity distribution patterns between white and gray matter in the Hoffman brain phantom were well imaged. These results demonstrate that the developed GAPD based brain PET system is useful for high quality brain PET imaging.
Starting Page	1
Ending Page	4
File Size	2046701
Page Count	4
File Format	PDF
e-ISBN	9781479905348
DOI	10.1109/NSSMIC.2013.6829113
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-10-27
Publisher Place	South Korea
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Positron emission tomography Detectors Sensitivity Spatial resolution Energy resolution Phantoms Timing
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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