NDLI: A first study on the timing performance of PMT-Quadrant-Sharing LYSO detector array for time-of-flight PET

Content Provider	IEEE Xplore Digital Library
Author	Shaohui An Hongdi Li Shitao Liu Ramirez, R. Yuxuan Zhang Baghaei, C. Wai-Hoi Wong
Copyright Year	2009
Description	Author affiliation: Department of Experimental Diagnostic Imaging, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030 USA (Shaohui An; Hongdi Li; Shitao Liu; Ramirez, R.; Yuxuan Zhang; Baghaei, C.; Wai-Hoi Wong)
Abstract	Time-of-flight (TOF) information can improve the imaging quality of positron emission tomography (PET) camera by calculating the original positron-electron annihilation position. In this work, we measured the preliminary TOF resolution of non-TOF-optimized LYSO arrays for TOF PET using our PMT-Quadrant-Sharing (PQS) technology which has higher light collection efficiency (no external light guide). We investigated digital signal processing methods that may achieve better time resolution. Digital oscilloscope Tektronix DPO7054 was used to capture the waveforms. Three timing methods, Linear Fitting (LF) to the pulse rising time, Constant Fraction Discriminator (CFD) and Leading edge Discriminator (LD), were studied. A new Time-Energy (T-E) correction using Multivariate Least Mean Square Fit was applied to minimize time walk caused by the variation of signal shape. The time resolution as a function of the depth of interaction was also studied. The average block-to-block coincident timing resolution of 13×13 (4×4×20 $mm^{3}$ detector pixel) array with fast PMT R9779 (51-mm diameter) was measured to be 432 ps (FWHM). Another 13×13 crystal array with ultrahigh spatial resolution 1.4×1.4×10 $mm^{3}$ detector pixels coupling to small 19-mm diameter poor-timing XP1912 PMTs was also tested and achieved 551 ps. This study shows that our regular PQS detector blocks (without optimization for TOF) have good TOF time resolution suitable for TOF PET systems, in addition to higher spatial resolution and reducing PMT cost.
Starting Page	3593
Ending Page	3596
File Size	728890
Page Count	4
File Format	PDF
ISBN	9781424439614
ISSN	10957863
DOI	10.1109/NSSMIC.2009.5401827
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-10-24
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Timing Detectors Sensor arrays Positron emission tomography Spatial resolution Signal resolution High-resolution imaging Cameras Optical arrays Digital signal processing time resolution time-of-flight PET LYSO arrays digital signal processing PMT-Quadrant-Sharing
Content Type	Text
Resource Type	Article

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