NDLI: rSPECT: A compact gamma camera based SPECT system for small-animal imaging

Content Provider	IEEE Xplore Digital Library
Author	Lage, E. Villena, J.L. Tapias, G. Vidal-Migallon, I. Abella, M. Sisniega, A. Martinez, N.P. Ros, D. Desco, M. Vaquero, J.J.
Copyright Year	2009
Description	Author affiliation: Unidad de Biofísica y Bioingeniería, Universidad de Barcelona- IDIBAPS. Spain (Martinez, N.P.; Ros, D.) \|\| Unidad de Medicina y Cirugía Experimental, Hospital General Universitario Gregorio Marañon, Madrid, Spain (Lage, E.; Villena, J.L.; Tapias, G.; Vidal-Migallon, I.; Abella, M.; Sisniega, A.; Desco, M.; Vaquero, J.J.)
Abstract	We have developed a compact and modular gamma camera system and assessed its performance when used on a small-animal SPECT prototype (rSPECT). Each camera consists of a Hamamatsu H-8500 position sensitive photomultiplier tube coupled to a 30 × 30 NaI (Tl) scintillator array (1.4mm × 1.4mm × 6mm crystal size) and electronics for pre-processing and matching the detector signals to an in-house developed data acquisition system. The camera components are enclosed in a lead-shielded case with a receptacle to insert the collimators (parallel-hole or pinhole with different tungsten apertures). System performance has been assessed for a low energy high resolution parallel-hole collimator (LEHR), and for a 0.75 mm pinhole collimator with 60º aperture angle. In this paper we present details on the system implementation and results of performance measurements, as well as first tomographic images on phantoms and animals. This SPECT was conceived for compactness and cost-effective routine small-animal imaging, and acquisitions of living mice and rats carried out with the system demonstrate its ability to provide useful high-resolution images for in vivo research.
Starting Page	3126
Ending Page	3131
File Size	373611
Page Count	6
File Format	PDF
ISBN	9781424439614
ISSN	10957863
DOI	10.1109/NSSMIC.2009.5401682
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-10-24
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Cameras Optical imaging Collimators Apertures Prototypes Photomultipliers Electron tubes Sensor arrays Position sensitive particle detectors Signal detection gamma camera Single Photon Emission Computed Tomography (SPECT) small-animal imaging
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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