NDLI: A simple and improved digital timing method for positron emission tomography

Content Provider	IEEE Xplore Digital Library
Author	Hu, W. Choi, Y. Jung, J.H. Kang, J.H. Min, B.J. Huh, Y.S. Shin, S.H. Lim, H.K. Chung, Y.H.
Copyright Year	2009
Description	Author affiliation: Department of Radiological Science, Yonsei University College of Health Science, 234 Meaji, Heungup Wonju, Kangwon-Do, 220-710, Republic of Korea (Chung, Y.H.) \|\| Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 135-710, Republic of Korea (Hu, W.; Choi, Y.; Jung, J.H.; Kang, J.H.; Min, B.J.; Huh, Y.S.; Shin, S.H.; Lim, H.K.)
Abstract	A simple and improved digital timing method has been developed for positron emission tomography (PET). The so-called initial rise interpolation method is based on an important characteristic of gamma signal: a properly pre-amplified and sampled gamma signal pulse can be characterized to arrive with an initial rise from baseline and then to go up with a maximum rise. Pulse arrival time is obtained by calculating the intersection of the initial rise line with the baseline for each gamma signal pulse. In this study, a FPGA-based data acquisition (DAQ) card was used for data acquisition and processing. We measured coincidence timing resolution of two types (fast and slow) of recently developed 3 mm × 3 mm Geiger mode avalanche photodiodes (GAPDs) using 3 different digital timing methods: initial rise interpolation (IRI), digital CFD and maximum rise interpolation (MRI). Furthermore, simulation has been performed to evaluate effects of pulse rise time, pulse amplitude and front-end noise level on timing resolution estimated by the three digital timing methods. Measured results show that, IRI method provided the best timing resolution for both types of GAPDs: 0.7 ns FWHM for fast GAPD and 1.5 ns for slow GAPD (digital CFD: 1.5 ns and 2.2 ns; MRI: 1.8 ns and 2.7 ns). In accordance with measured results, simulation results also show that IRI method provided the best timing resolution. Based on these experimental results, we concluded that the developed simple and improved digital timing method is reliable and useful for the development of high performance PET.
Starting Page	3893
Ending Page	3896
File Size	1193531
Page Count	4
File Format	PDF
ISBN	9781424439614
ISSN	10957863
DOI	10.1109/NSSMIC.2009.5401926
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-10-24
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Timing Positron emission tomography Interpolation Data acquisition Computational fluid dynamics Magnetic resonance imaging Signal resolution Avalanche photodiodes Performance evaluation Noise level Geiger mode avalanche photodiode (GAPD) Digital timing method Field-programmable gate array
Content Type	Text
Resource Type	Article

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