NDLI: Towards a generic respiratory motion model for 4D CT imaging of the thorax

Content Provider	IEEE Xplore Digital Library
Author	Fayad, H. Clement, J.F. Pan, T. Roux, C. Le Rest, C.C. Pradier, O. Visvikis, D.
Copyright Year	2009
Description	Author affiliation: M.D. Anderson Cancer Center, Houston, Texas, USA (Pan, T.) \|\| INSERM U650, Laboratoire du Traitement de lInformation Mdicale (LaTIM), Brest, F-29200 France (Roux, C.) \|\| INSERM U650, Laboratoire du Traitement de lInformation Mdicale (La-TIM), Brest, F-29200 France (Fayad, H.; Clement, J.F.; Le Rest, C.C.; Pradier, O.) \|\| INSERM U650, Laboratoire du Traitement de lInfor-mation Mdicale (LaTIM), Brest, F-29200 France (Visvikis, D.)
Abstract	One of the most important parameters reducing the sensitivity and specificity in the thoracic and abdominal areas is respiratory motion and associated deformations which represent today an important challenge in medical imaging. The negative impact of respiratory motion is not only evident in the field of cancer diagnostic imaging but also in therapy applications, particularly in the field of radiation therapy. Modelling of the respiratory motion is therefore very important for the efficacy of both diagnostic and therapeutic imaging applications. All respiratory motion models presented to date are patient specific and require a 4D CT acquisition for every patient implying an associated increased dose which cannot be easily justified for all patients. The objective of this study is the description of a framework for the creation of a global generic model from 4D CT images of different patients. This global model is based on principal component analysis (PCA) and can be adapted to a given patient anatomy needing only one static CT image in combination with respiratory synchronised images of the patient surface. In this work 4D CT images of three patients were used to create the model which was tested by subsequently adapting it on the static CT images of two different patients. Our comparative results between the model derived and the corresponding acquired 4D CT images demonstrate the efficiency of the developed generic motion model.
Starting Page	3975
Ending Page	3979
File Size	242218
Page Count	5
File Format	PDF
ISBN	9781424439614
ISSN	10957863
DOI	10.1109/NSSMIC.2009.5401945
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-10-24
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Computed tomography Thorax Principal component analysis Sensitivity and specificity Abdomen Biomedical imaging Cancer Medical treatment Biomedical applications of radiation Anatomy
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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