NDLI: Multidimensional B-spline parameterization of the detection probability of the PET scanner Biograph 16 using GATE

Content Provider	IEEE Xplore Digital Library
Author	Rehfeld, N.S. Vauclin, S. Stute, S. Buvat, I.
Copyright Year	2009
Description	Author affiliation: IMNC-UMR 8165 CNRS - Paris 7 University - Paris 11 University, 15 rue Georges Clémenceau, 91406 Orsay Cedex, France (Rehfeld, N.S.; Stute, S.; Buvat, I.) \|\| LITIS EA Laboratory, University of Rouen, Rouen, France (Vauclin, S.)
Abstract	GATE (Geant4 Application for Emission Tomography) [1] is a widespread, well validated and very versatile application for Monte Carlo simulations in emission tomography. It allows very detailed simulations of positron emission tomography (PET) or single photon emission computed tomography (SPECT) scanners using the general purpose Monte Carlo code Geant4 [2], [3]. We present a method to accelerate GATE simulations when on the one hand the detection probability in the different crystals needs to be computed accurately taking into account the complex geometry of the detection system and on the other hand information on photon statistics is not required. The simulation is split into two parts. Inside the scanner (phantom or voxelized patient) the particles are tracked conventionally. When a particle leaves the phantom, the particle is transported to a virtual boundary that replaces the detection system in the simulation and the detection proability is calculated analytically by evaluating a multi-dimensional B-spline function taking into account the state of the photon on this virual border (position, incident angles, energy). The B-spline function itself is calculated by performing a conventional Monte Carlo simulation. This “pre”-simulation needs to be performed only once for each scanner type. The presented method was tested by simulating the PET scanner Biograph HiREZ and using a realistic voxelized attenuation phantom. The results show good agreement between conventional GATE simulations and simulations using the B-spline. The simulations could be accerelated by a factor of around 23 yielding the same statistical accuracy.
Starting Page	4197
Ending Page	4200
File Size	302181
Page Count	4
File Format	PDF
ISBN	9781424439614
ISSN	10957863
DOI	10.1109/NSSMIC.2009.5402443
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-10-24
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Multidimensional systems Spline Positron emission tomography Computational modeling Single photon emission computed tomography Imaging phantoms Acceleration Probability Photonic crystals Monte Carlo methods
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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