NDLI: High performance SPECT camera design

Content Provider	IEEE Xplore Digital Library
Author	Dey, J.
Copyright Year	2009
Description	Author affiliation: Department of Radiology, University of Massachusetts Medical School, Worcester, MA, 01655 (Dey, J.)
Abstract	SPECT is primarily used in the clinic for cardiac applications like myocardial perfusion imaging (MPI). However, for SPECT, sensitivity is impaired due to the need for collimation. System resolution is poor as well (FWHM~1cm). New SPECT camera designs have emerged with improved sensitivity over the standard gamma cameras currently used in the clinic for estimating myocardial perfusion. Most of them focus on a region around the heart. The UFC design from GE or the multi-pinhole design by Funk et al use stationary pinholes configurations. The advantages of pin-hole designs are that there are no moving parts reducing long-term servicing costs. We propose a novel design to improve resolution and/or sensitivity over the flat-detector multi-pinhole designs by using curved detectors fitted to pin-holes. This will obtain improved resolution over that of a flat-detector attached to the same pin-hole due to increased magnification. We can then trade-off sensitivity versus resolution to get increased sensitivity for similar resolution as the flat-detector (by increasing the hole diameter). We derived expressions for average resolution for paraboloid, conical, and spherical detectors. We simulated the resolution and sensitivity improvement for examples cases for paraboloid, conical and spherical detectors for a stationary configuration of pinholes focused in a region in the object space, designed for cardiac application. For a paraboloid design, for cardiac SPECT application, the estimated sensitivity improvement over a multi-pin-hole system by Funk et al, was 48-85% for similar resolution. For a conical design, the improvement was 40-75%. The sensitivity improvement of the curved detector system over the clinical systems currently used in the clinic for cardiac imaging (using LEHR parallel collimation) was a factor of 7.4 to 9.3 for paraboloid (and 7 to 9 times for conical), with resolutions close to that of LEHR parallel collimation in the region of interest. Further there are tunable surface-parameters (such as height) if application calls for greater sensitivity and/or resolution, without changing the compactness (base-diameter) of the design. Finally, the performance of the paraboloid and conical design was better than the spherical design for this application, which suggests there may exist an optimum surface of the curved detector yielding the best improvement of resolution and/or sensitivity.
Starting Page	2605
Ending Page	2616
File Size	2762160
Page Count	12
File Format	PDF
ISBN	9781424439614
ISSN	10957863
DOI	10.1109/NSSMIC.2009.5402009
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-10-24
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Cameras Detectors Collimators Myocardium High-resolution imaging Optical imaging Heart Costs Object detection Focusing
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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