NDLI: MR insertable brain PET using tileable GAPD arrays

Content Provider	IEEE Xplore Digital Library
Author	Key Jo Hong Yong Choi Jin Ho Jung Jihoon Kang Wei Hu Hyun Keong Lim Yoonsuk Huh Sangsu Kim Ji Woong Jung Kyu Bom Kim Myung Sung Song Hyun-wook Park
Copyright Year	2010
Description	Author affiliation: fMRI Laboratory N23, Department of Electrical Engineering, Korea Advanced Institute of Science and Technology, 373-1, Guseong-dong, Yuseong-gu, Daejeon, 305-701, Republic of Korea (Myung Sung Song; Hyun-wook Park) \|\| Department of Electronic Engineering, Sogang University, 1 Shinsu-Dong, Mapo-Gu, Seoul, 121-742, Republic of Korea (Key Jo Hong; Yong Choi; Jin Ho Jung; Jihoon Kang; Wei Hu; Hyun Keong Lim; Yoonsuk Huh; Sangsu Kim; Ji Woong Jung; Kyu Bom Kim)
Abstract	The aim of this study is to develop a MR compatible PET that is insertable to MRI and allows simultaneous PET and MR imaging of human brain. The brain PET having 72 detector modules arranged in a ring of 330 mm diameter was constructed and mounted in a 3-T MRI. Each PET module composed of 4 × 4 matrix of 3 mm × 3 mm × 20 mm LYSO crystals coupled to a tileable 4 × 4 array Geiger-mode avalanche photodiode (GAPD) and designed to locate between RF and gradient coils. GAPD output charge signals were transferred to preamplifiers using flat cable of 3 m long, and then sent to position decoder circuit (PDC) identifying digital address and generating an analog pulse of the one interacted channel from preamplifier signals. The PDC outputs were fed into FPGA-embedded DAQ boards. The analog signal was digitized, and arrival time and energy of the signal were calculated and stored. LYSO and GAPD were located inside MR bore and all electronics including preamplifiers were positioned outside MR bore to minimize signal interference between PET and MR. Simultaneous PET/MR images of a hot-rod and Hoffman brain phantom were acquired in a 3-T MRI using the MR compatible PET system. The rods down to a diameter of 3.5 mm were resolved in the hot-rod PET image. Activity distribution patterns between white and gray matter in Hoffman brain phantom were well imaged. No degradation of image quality of the hot-rod and Hoffman brain phantoms on the simultaneously acquired MR images obtained with standard sequences was observed. These results demonstrate that simultaneous acquisition of PET and MR images is feasible using the MR insertable PET developed in this study.
Starting Page	2016
Ending Page	2019
File Size	1818864
Page Count	4
File Format	PDF
ISBN	9781424491063
ISSN	10957863
e-ISBN	9781424491056
DOI	10.1109/NSSMIC.2010.5874130
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-10-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Positron emission tomography Magnetic resonance imaging Imaging phantoms Detectors Preamplifiers Three dimensional displays
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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