NDLI: TOF-PET small-lesion image quality measured over a range of phantom sizes

Content Provider	IEEE Xplore Digital Library
Author	Wilson, J.M. Turkington, T.G.
Copyright Year	2009
Description	Author affiliation: Duke University Graduate Program in Medical Physics, Durham, NC, USA (Wilson, J.M.) \|\| Radiology Department, Duke University Medical Center, Durham, NC 27710, USA (Turkington, T.G.)
Abstract	The purpose of this study was to parameterize TOF image quality improvement over non-TOF PET using small lesions in a tapering phantom that represents a range of body sizes. A set of 46 1.0-cm spherical inserts was divided into 6 groups and positioned in a fillable, tapered phantom that represents a range of body dimensions (an oval cross section from 38.5 cm × 49.5 cm to 6.8 cm × 17.8 cm with a length of 51.1 cm). The hot spheres were positioned in a uniform warm background (8:1 radioactivity concentration) and were distributed in 6 regions of different cross-sectional areas: 6 spheres at 306 $cm^{2},$ and 8 spheres at 426, 574, 754, 964, and 1187 $cm^{2}.$ The PET/CT study was acquired on a Discovery 690 PET/CT (GE Healthcare), which uses LYSO crystals (4.25 × 6.3 × 25 $mm^{3})$ in three rings of 6 × 9 blocks. Six frames, with a different set of spheres centered for each frame, were each acquired. Images were reconstructed with and without TOF information using 3D OSEM with 8 subsets and 1–20 iterations. The 50-cm field of view (FOV) was reconstructed to a 128×128 matrix with attenuation, normalization, decay, scatter, singles-based random corrections, and z-axis smoothing, but no post-filter was applied. An automated algorithm was used to locate and place regions of interest on the hot spheres in the CT, and then apply the ROIs to the PET images to measure signal and background variability (image noise). When both TOF and non-TOF images are near convergence, the ratio of contrast recovery for TOF to non-TOF is ~1.0 for small body sizes, but the CRC increase ranges from 10%–25% for body sizes with diameters >30.0 cm. When comparing the small lesion signal-to-noise ratios between TOF and non-TOF images, the square of the SNR ratios for TOF to non-TOF was a function of body size and timing resolution with an offset of -1.36.
Starting Page	3710
Ending Page	3714
File Size	1383071
Page Count	5
File Format	PDF
ISBN	9781424439614
ISSN	10957863
DOI	10.1109/NSSMIC.2009.5401866
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-10-24
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Image quality Size measurement Imaging phantoms Positron emission tomography Computed tomography Lesions Image reconstruction Medical services Crystals Attenuation
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

TOF-PET Small-Lesion Image Quality Measured Over a Range of Phantom Sizes

Quantitative bias in PET/MR from attenuation correction and reconstruction: A comparison with PET and PET/CT with an anatomical brain phantom and Hoffman brain phantom

Development of a fillable, tapered PET/CT phantom

ROC analysis of PET imaging performance of two PET/CT scanners based on lesion detectability in a torso phantom

A Comparison of Five Whole-Body PET Scanners by Scanning Hoffman Brain Phantom

Quantitative imaging with low-dose CT in the PET/CT system

Characteristics of PET/CT images of the ACR PET phantom

CT-based attenuation correction in PET image reconstruction for the Gemini system

Development of a phantom to simulate a wide range of body sizes

TOF-PET small-lesion image quality measured over a range of phantom sizes

Similar Documents

TOF-PET Small-Lesion Image Quality Measured Over a Range of Phantom Sizes

Quantitative bias in PET/MR from attenuation correction and reconstruction: A comparison with PET and PET/CT with an anatomical brain phantom and Hoffman brain phantom

Development of a fillable, tapered PET/CT phantom

ROC analysis of PET imaging performance of two PET/CT scanners based on lesion detectability in a torso phantom

A Comparison of Five Whole-Body PET Scanners by Scanning Hoffman Brain Phantom

Quantitative imaging with low-dose CT in the PET/CT system

Characteristics of PET/CT images of the ACR PET phantom

CT-based attenuation correction in PET image reconstruction for the Gemini system

Development of a phantom to simulate a wide range of body sizes

TOF-PET small-lesion image quality measured over a range of phantom sizes