NDLI: A Self-Normalization Reconstruction Technique for PET Scans Using the Positron Emission Data

Content Provider	IEEE Xplore Digital Library
Author	Salomon, A. Goldschmidt, B. Botnar, R. Kiessling, F. Schulz, V.
Copyright Year	1982
Abstract	Positron emission tomography (PET) image quality in both clinical and preclinical environments highly depends on an accurate knowledge of the detector hardware to correct for image quality degrading effects like gain, temperature, and photon detection efficiency variations of the individual crystals. In conventional PET systems some of these variations are typically corrected using a dedicated calibration scan in which the scanner performance for a well-known activity source is measured. We propose an alternative method for estimating the relative sensitivity of each detector pixel using the coincidences as well as the singles emission data of each PET scan. The overall idea is to compare the total sum of all measured single photons before coincidence processing in each crystal with a steadily low-frequent distribution that can normally be expected. Both the estimated activity and the estimated detector sensitivity are simultaneously improved by using an extended iterative reconstruction scheme. This way we ensure the use of an optimal calibration correction (with the exception of a global factor) for each data set, even if the scanner performance has changed between two scans. Data measured with a preclinical PET scanner (HYPERIon-I) which uses analog silicon photomultipliers in combination with a custom-made ASIC shows a significant increase of image quality and homogeneity using the proposed method.
Sponsorship	IEEE Engineering in Medicine and Biology Society IEEE Nuclear and Plasma Sciences Society IEEE Signal Processing Society IEEE Ultrasonics, Ferroelectrics, and Frequency Control Society
Page Count	7
File Size	2950813
Starting Page	2234
Ending Page	2240
File Format	PDF
ISSN	02780062
Volume Number	31
Issue Number	12
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-12-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Crystals Detectors Positron emission tomography Integrated circuits Image reconstruction Sensitivity Phantoms scanner normalization HYPERImage positron emission tomography (PET) positron emission tomography/magnetic resonance (PET/MR) preclinical reconstruction scanner calibration
Content Type	Text
Resource Type	Article
Subject	Electrical and Electronic Engineering Computer Science Applications Radiological and Ultrasound Technology Software

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Comparison of Normalization Methods for ${^{124}}{rm I}$ PET on Siemens Inveon PET Scanner

Study-Parameter Impact in Quantitative 90-Yttrium PET Imaging for Radioembolization Treatment Monitoring and Dosimetry

ML-Reconstruction for TOF-PET With Simultaneous Estimation of the Attenuation Factors

PET Performance Evaluation of a Pre-Clinical SiPM-Based MR-Compatible PET Scanner

Completion of a Truncated Attenuation Image From the Attenuated PET Emission Data

A New Component Approach to Efficiency Normalization for 3D PET

Simultaneous MR-Compatible Emission and Transmission Imaging for PET Using Time-of-Flight Information

Analysis and Correction of Count Rate Reduction During Simultaneous MR-PET Measurements With the BrainPET Scanner

A Digital Preclinical PET/MRI Insert and Initial Results

A Self-Normalization Reconstruction Technique for PET Scans Using the Positron Emission Data

Similar Documents

Comparison of Normalization Methods for ${^{124}}{rm I}$ PET on Siemens Inveon PET Scanner

Study-Parameter Impact in Quantitative 90-Yttrium PET Imaging for Radioembolization Treatment Monitoring and Dosimetry

ML-Reconstruction for TOF-PET With Simultaneous Estimation of the Attenuation Factors

PET Performance Evaluation of a Pre-Clinical SiPM-Based MR-Compatible PET Scanner

Completion of a Truncated Attenuation Image From the Attenuated PET Emission Data

A New Component Approach to Efficiency Normalization for 3D PET

Simultaneous MR-Compatible Emission and Transmission Imaging for PET Using Time-of-Flight Information

Analysis and Correction of Count Rate Reduction During Simultaneous MR-PET Measurements With the BrainPET Scanner

A Digital Preclinical PET/MRI Insert and Initial Results

A Self-Normalization Reconstruction Technique for PET Scans Using the Positron Emission Data