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| Content Provider | PubMed Central |
|---|---|
| Author | Huang, Hai-jian Bao, Yan-yuan Lao, Shu-hua Huang, Xiao-hui Ye, Yi-zhou Wu, Jian-xiang Xu, Hai-jun Zhou, Xue-ping Zhang, Chuan-xi |
| Copyright Year | 2015 |
| Abstract | Most plant viruses that seriously damage agricultural crops are transmitted byinsects. However, the mechanisms enabling virus transmission by insect vectors arepoorly understood. The brown planthopper (Nilaparvata lugens) is one of themost serious rice pests, causing extensive damage to rice plants by sucking thephloem sap and transmitting viruses, including Rice ragged stunt virus(RRSV). In this study, we investigated the mechanisms of RRSV transmission from itsinsect vector to the rice plant in vivo using the terminal deoxynucleotidyltransferase dUTP nick-end labeling assay and RNA interference technology. RRSVinduced apoptosis in the salivary gland cells of its insect vector, N.lugens. The RRSV-induced apoptosis was regulated through a caspase-dependentmanner, and inhibition of the expression of N. lugens caspase-1 genessignificantly interfered with virus transmission. Our findings establish a linkbetween virus-associated apoptosis and virus transmission from the insect vector tothe host plant. |
| Related Links | http://dx.doi.org/10.1038/srep11413 |
| Starting Page | 11413 |
| File Format | |
| ISSN | 20452322 |
| e-ISSN | 20452322 |
| Journal | Scientific Reports |
| Volume Number | 5 |
| Language | English |
| Publisher | Nature Publishing Group |
| Publisher Date | 2015-06-01 |
| Access Restriction | Open |
| Rights Holder | Nature Publishing Group |
| Subject Keyword | Science and technology Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Multidisciplinary |
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