NDLI: Half-millimeter animal SPECT imaging on a clinical SPECT scanner with highly flexible collimator design

Content Provider	IEEE Xplore Digital Library
Author	Tianyu Ma Tiantian Dai Hui Liu Junjian Cui Shi Wang Yangqiang Liu Qingyang Wei Jing Wu Yongjie Jin
Copyright Year	2010
Description	Author affiliation: Tsinghua University, China (Tianyu Ma; Tiantian Dai; Hui Liu; Junjian Cui; Shi Wang; Yangqiang Liu; Qingyang Wei; Jing Wu; Yongjie Jin)
Abstract	In order to develop animal SPECT imaging technology on clinical SPECT scanners, we propose a highly flexible multi-pinhole collimator design scheme. The proposed design allows individual adjustment of important system parameters, so that the collimator device is adaptable to various SPECT systems, and one can also optimize different specific aspects of system performance (e.g. improving spatial resolution, maximizing sensitivity or increasing FOV) for different application purposes. This work is focused on achieving half-mm SPECT imaging resolution on a single-head clinical SPECT scanner. A seven-pinhole collimator and a four-degree-offreedom motion control stage are assembled. High accuracy geometrical calibration is performed by scanning a point source in a hybrid orbit, which consists of three circular orbits in different axial positions and a helical orbit. The system matrix is derived from Monte-Carlo simulation and de-noised by fitting each point spread function (PSF) to a 2D Gaussian function. Dual-point-source studies show that 0.5 mm reconstruction resolution is achievable in the studied system. Preliminary ultra micro hot rod phantom experiments demonstrate 0.6 mm hot rods are identifiable clearly. The proposed technology is attractable for its low cost, high flexibility, high feasibility and reproducibility.
Starting Page	1
Ending Page	4
File Size	698602
Page Count	4
File Format	PDF
ISBN	9781424491063
ISSN	10957863
e-ISBN	9781424491056
DOI	10.1109/NSSMIC.2010.6036249
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-10-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Single photon emission computed tomography Collimators Orbits Calibration Animals Image reconstruction Detectors
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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