NDLI: Beyond list mode: On-line rebinning and histogramming for continuous bed motion in clinical whole-body TOF PET/CT

Content Provider	IEEE Xplore Digital Library
Author	Jones, W.F. Breeding, E. Reed, J.H. Luk, W. Moor, A. Townsend, D.
Copyright Year	2010
Description	Author affiliation: Siemens Molecular Solutions, Knoxville, TN 37932 USA (Jones, W.F.; Breeding, E.; Reed, J.H.; Luk, W.; Moor, A.; Townsend, D.)
Abstract	In this article, methods are described which help move the concept of continuous bed motion (CBM) for TOF PET (i.e. for PET/CT applications) out of the realm of list-mode-only research and into everyday clinical usage. Long proposed for PET, CBM moves the patient horizontally (at a more or less steady rate) through the PET FOV during the acquisition and offers several points of advantage over the more common patient-held-stationary-to-PET-FOV approach. One primary obstacle to frequent clinical application of CBM in PET has been the inability to provide on-line, real-time detector-pair-to-projection-space-bin-address rebinning calculations along with the associated on-line histogramming. Here are presented details for one approach to overcome just such obstacles — significantly allowing the on-line generation of single TOF projection data sets which may each represent an entire whole-body scan. A set of 5 real list-mode data files were collected from a TOF PET/CT — a system which has been outfitted with a patient handling system (PHS or “bed”) which is shown to be largely sufficient for CBM in PET. For an F-18 point source — placed for first a 1cm and then a 10cm transaxial offset, list-mode data was collected for both stationary and horizontal bed motion cases. In addition, a CBM list-mode data set was collected for a custom, F-18, 100cm-long, cylindrical phantom. These data sets were processed in a manner computationally equivalent to that proposed for the realtime, on-line processing case. By comparing stationary to CBM image quality, the resulting analysis strongly suggests these proposed methods will provide real-time CBM processing which is compatible with the needs of clinical-grade TOF PET. As perhaps expected from CBM, the Z-axis FWHM is shown to generally improve over the stationary case via finer axial sampling in the rebinning step. As may be atypical, one specific data point showed a Z-axis improvement of 6.5%. Other examples — which may be more typical — showed little or no Z-axis FWHM improvement when applying CBM.
Starting Page	3113
Ending Page	3117
File Size	3422815
Page Count	5
File Format	PDF
ISBN	9781424491063
ISSN	10957863
e-ISBN	9781424491056
DOI	10.1109/NSSMIC.2010.5874373
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-10-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Positron emission tomography Image resolution Computed tomography Synthetic aperture sonar Data acquisition Pixel Field programmable gate arrays
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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