NDLI: Longitudinal registration of liver PET scans using four phase CT

Content Provider	IEEE Xplore Digital Library
Author	Wentao Zhu Leahy, R.M. Conti, P.S. Quanzheng Li
Copyright Year	2010
Description	Author affiliation: University of Southern California, LA, CA 90089 USA (Wentao Zhu; Leahy, R.M.; Quanzheng Li) \|\| PET Imaging Science Center, University of Southern California, LA, CA 90033 USA (Conti, P.S.)
Abstract	We have developed an image registration approach for longitudinal liver PET studies using the anatomical information in two sets of associated four phase CT images. We first used the level set method to segment the whole liver in the venous phase CT image. We then applied a non-rigid mutual information based method to register the two venous phase liver images. In our data acquisition protocol, the four phase CT and PET/CT images of the patient are acquired in the same scanning session so can be co-registered using rigid registration. We finally combined the non-rigid registration of 2 set of four phase CT images at different time points with the 2 rigid registrations between corresponding PET/CT and four phase CT image. The result was a single non-rigid transformation between longitudinal pairs of PET images. The method is for use in tracking disease progression and treatment in colon cancer patients with metastatic liver disease. We illustrate the method using a clinical dataset.
Starting Page	2366
Ending Page	2369
File Size	453789
Page Count	4
File Format	PDF
ISBN	9781424491063
ISSN	10957863
e-ISBN	9781424491056
DOI	10.1109/NSSMIC.2010.5874209
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-10-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Computed tomography Liver Positron emission tomography Spline Pixel Image registration Mutual information
Content Type	Text
Resource Type	Article

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