NDLI: The engineering design and construction of an ultra-high resolution high-sensitivity preclinical PET/CT

Content Provider	IEEE Xplore Digital Library
Author	Yuxuan Zhang Ramirez, R. Hongdi Li Shitao Liu Shaohui An Chao Wang Baghaei, H. Wai-Hoi Wong
Copyright Year	2010
Description	Author affiliation: University of Texas M. D. Anderson Cancer Center, Houston, Texas, 77030, USA (Yuxuan Zhang; Ramirez, R.; Hongdi Li; Shitao Liu; Shaohui An; Chao Wang; Baghaei, H.; Wai-Hoi Wong)
Abstract	An ultra-resolution high-sensitivity preclinical PET/CT — MuPET is designed and manufactured. The detector system is a triacontagon shape which is very close to a perfect cylindrical ring. The inner diameter of the ring is 165 mm and the axial length is 116 mm. The detector system is using 180 PMT-quadrant-sharing (PQS) blocks — 30 blocks per ring and 6 rings axially with 210 low-cost round PMTs for PQS decoding. Each block consists of 169 LYSO crystals in a 13×13 array. The Slab-Sandwich-Slab (SSS) production methodology is used for the mass production of the 19×19×10 $mm^{3}$ cuboid blocks. The cuboid blocks are then ground into pentagon shape with a taper angle of 6° at the two side faces, which can eliminate the wedge shape gaps between blocks inside the detector ring to increase the sensitivity. Two crystal widths are used: the small one of 1.32 mm for the 11 crystals in the middle and the large one of 1.76 mm for the 2 crystals on both sides. Using large crystal size can compensate the volume loss due to the grinding, thus improve the uniformity of the individual crystal sensitivities which will benefit the data acquisition and processing. The no-gap detector ring is finished and mounted on the coliseum shape PMT holder with high accuracy. 210 Hamamatsu R1450 19-mm PMTs are selected and sorted base on their gain and dark current, and optical coupled to the detector ring. High voltage dividers and front-end electronics are also mounted inside the PET unit enclosure. The assembled PET module is then inserted into an existing PET/CT gantry which has a cone beam CT installed already. The new PET/CT system is under system debugging and tuning. The preliminary testing results show 5% sensitivity with energy window of 300 to 650 keV, which has the potential to be improved further. The resolution is better than 1.3 mm near the FOV center and the high quality Micro-Deluxe phantom image is obtained.
Starting Page	2602
Ending Page	2606
File Size	580507
Page Count	5
File Format	PDF
ISBN	9781424491063
ISSN	10957863
e-ISBN	9781424491056
DOI	10.1109/NSSMIC.2010.5874259
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-10-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Detectors Crystals Positron emission tomography Computed tomography Shape Spatial resolution Sensitivity
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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