NDLI: Spatial resolution performance and object detection improvement with a multiple-wavelength NIR light transmission scanner

Content Provider	IEEE Xplore Digital Library
Author	Uzunov, N.M. Bello, M. Moschini, G. Rossi, P. Rosato, A. Rondina, M.B. Montagner, I.M. Boldrin, D. Muzzio, P.C.
Copyright Year	2010
Description	Author affiliation: Department of Physics, University of Padua, and INFN, section of Padua, 35128 Padua, Italy (Rossi, P.) \|\| Veneto Institute of Oncology IRCCS, 35128 Padua, Italy (Rosato, A.; Muzzio, P.C.) \|\| Dept. of Oncology and Surgical Sciences, University of Padua, 35128 Padua, Italy (Rondina, M.B.; Montagner, I.M.; Boldrin, D.) \|\| National Laboratories of Legnaro, INFN, 35020 Legnaro (PD) Italy, on leave from the Department of Natural Sciences of the University of Shumen, Shumen 9715 Bulgaria (Uzunov, N.M.) \|\| Department of Physics, University of Padua, and National Laboratories of Legnaro, INFN, 35020 Legnaro (PD) Italy (Bello, M.; Moschini, G.)
Abstract	A multiple-wavelength near-infrared (NIR) imaging device has been constructed. The scanner utilizes transmitted through the objects NIR light at five different wavelengths in the interval of 900nm–1600nm. The scanning is realized by a consecutive positioning of Hamamatsu G9203–256D InGaAs linear image sensor sliding close to the scanned object and results in a set of five object's images. The scanned region has a rectangular shape with dimensions of 50mm × 80mm. A system of polarizers ensures scanning of the objects in polarized NIR light as well. The number of object images obtained at different wavelengths and at different angles of the transmitted NIR light makes possible the application of a multivariate image analysis (MIA) in order to reveal tissue objects whose NIR light absorption exhibits slight deviations from the rest of the media. In this article we present results from the spatial resolution measurements conducted with the scanner as well as a spectral analysis of the transmittance of NIR in some mice tissues. A multivariate image analysis has been conducted on NIR images of mice tumor tissues taken at different wavelengths. The resulted images from the MIA projection back compare well with the observations from alternative methods.
Starting Page	2587
Ending Page	2590
File Size	3662565
Page Count	4
File Format	PDF
ISBN	9781424491063
ISSN	10957863
e-ISBN	9781424491056
DOI	10.1109/NSSMIC.2010.5874255
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-10-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Spatial resolution Mice Light emitting diodes Pixel Lungs Liver Tumors
Content Type	Text
Resource Type	Article

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