NDLI: Efficient system modeling of a high-resolution zoom-in PET scanner

Content Provider	IEEE Xplore Digital Library
Author	Jian Zhou Jinyi Qi
Copyright Year	2010
Description	Author affiliation: Department of Biomedical Engineering, University of California, Davis, CA 95616, USA (Jian Zhou; Jinyi Qi)
Abstract	We have proposed a “zoom-in” PET system that integrates a higher-resolution detector capable of measuring depth of interaction (DOI) into an existing scanner to obtain highresolution images of a targeted region with high-sensitivity. The system acquires coincidence events between the high-resolution detector and low-resolution detectors, as well as those between the low-resolution detectors. Because of the irregular system geometry and the use of a DOI detector, the system matrix of the zoom-in PET system requires far greater storage space than that of a conventional PET scanner, which also results in long computational time for image reconstruction. To address this issue, here we propose a system matrix factorization for the zoom-in PET to reduce the storage and computational cost while maintaining the accuracy in image reconstruction. The proposed factored system matrix consists of two major components: a detector response (or sinogram blurring) matrix and a geometrical projection matrix. We present a novel method to design the geometrical component and an iterative algorithm to estimate the detector response matrix. A 2D simulation study showed that the proposed method can reduce the storage space and reconstruction time by a factor of 5 without noticeable sacrifice in image quality.
Starting Page	3501
Ending Page	3505
File Size	528516
Page Count	5
File Format	PDF
ISBN	9781424491063
ISSN	10957863
e-ISBN	9781424491056
DOI	10.1109/NSSMIC.2010.5874457
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-10-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Detectors Positron emission tomography Image reconstruction Noise measurement Image resolution Geometry Bismuth
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
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9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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