NDLI: CT-based evaluation of segmented head regions for attenuation correction in MR-PET systems

Content Provider	IEEE Xplore Digital Library
Author	Wagenknecht, G. Kops, E.R. Kaffanke, J. Tellmann, L. Mottaghy, F. Piroth, M.D. Herzog, H.
Copyright Year	2010
Description	Author affiliation: Department of Radiotherapy, University Hospital Aachen, Germany (Piroth, M.D.) \|\| Central Institute for Electronics, Research Center Juelich, Germany (Wagenknecht, G.) \|\| Institute of Neuroscience and Medicine-4, Research Center Juelich, Germany (Kops, E.R.; Kaffanke, J.; Tellmann, L.; Herzog, H.) \|\| Department of Nuclear Medicine, University Hospital Aachen, Germany (Mottaghy, F.)
Abstract	Attenuation correction (AC) is an important prerequisite for quantitative brain PET in MR-BrainPET systems. The new knowledge-based method segments attenuation-differing head regions solely based on the routinely acquired T1-weighted MR data set of the patient's head. The original approach (O) was extended (E1-E3) with regard to the MR image quality at different bandwidth/voxel (130 HZ/voxel, 610 Hz/voxel) obtained at a 3T MR TimTrio system with BrainPET insert installed. Based on the Dice coefficient, the automatically obtained MR-based segmentation results for bone and soft tissue were compared with segmented CT data as gold standard modality data. So far, registered multi-modality data (MR, CT, PET) are available for one female volunteer F and two tumor patients T1, T2 with CT data of different image quality. Best results were obtained for BW130-E3 and BW610-E2. For F, the Dice coefficient for bone is up to 0.776 for BW130-E3 and up to 0.723 for BW610-E2 in the best part of the cranial region. The Dice coefficient for soft tissue is 0.867 for BW130-E3 and 0.868 for BW610-E2 in the whole data set used for AC. The SegMR-(SBA) and CT-based AC (CBA) were compared w.r.t. PET-based AC (PBA) for a HR+ PET device. AC with SBA yields very similar results to the gold standard CBA.
Starting Page	2793
Ending Page	2797
File Size	587173
Page Count	5
File Format	PDF
ISBN	9781424491063
ISSN	10957863
e-ISBN	9781424491056
DOI	10.1109/NSSMIC.2010.5874301
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-10-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Bones Computed tomography Image segmentation Positron emission tomography Attenuation Head Biological tissues CT-based evaluation MR-BrainPET attenuation correction head segmentation
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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