NDLI: A comparison of monodomain and bidomain propagation models for the human heart

Content Provider	IEEE Xplore Digital Library
Author	Potse, M. Dube, B. Vinet, A. Cardinal, R.
Copyright Year	2006
Description	Author affiliation: Res. Center, Hosp. du Sacre-Coeur de Montreal, Que. (Potse, M.; Dube, B.; Vinet, A.; Cardinal, R.)
Abstract	A bidomain reaction-diffusion model of the human heart was developed and potentials resulting from normal depolarization and repolarization were compared with results from a compatible monodomain model. Comparisons were made for an empty isolated heart and for a heart with fluid-filled ventricles. Both sinus rhythm and ectopic activation were simulated. The model took 2 days on 32 processors to simulate a complete cardiac cycle. Differences between monodomain and bidomain results were very small, even for the extracellular potentials which, for the monodomain model, were computed with a high-resolution forward model. Electrograms computed with monodomain and bidomain models were visually indistinguishable. We conclude that, in the absence of applied currents, propagating action potentials on the scale of a human heart can be studied with a monodomain model
Sponsorship	IEEE EMB
Starting Page	3895
Ending Page	3898
File Size	398134
Page Count	4
File Format	PDF
ISBN	1424400325
ISSN	1557170X
DOI	10.1109/IEMBS.2006.259484
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-08-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Humans Heart Extracellular Virtual manufacturing Computational modeling Biomembranes Equations Rhythm Cardiac tissue Cities and towns
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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