NDLI: Simulation of biochemical networks - Cellular networks as dynamic control systems

Content Provider	IEEE Xplore Digital Library
Author	Sauro, H.M.
Copyright Year	2006
Description	Author affiliation: Keck Graduate Inst., Claremont, CA (Sauro, H.M.)
Abstract	It has been appreciated for at least a hundred years that biological organisms contain control systems that enable them to adapt to a changing environment and adjust their internal systems when they need to proliferate. Even so, we have little understanding of the role that many of the control systems play. It's only in recent years that mainstream science has begun to study biological systems qualitatively and to look specifically at dynamical responses. As a result it might be possible that future cancer therapies will operate by manipulating the control systems that have gone awry during uncontrolled proliferation. This is a long term goal because it would require a mind shift in the way some biologists approach such problems. In this short paper the author describes some of the main control elements found in biological systems and illustrate their use in biological networks. In addition the author discuss some of the strategies that one can use to build computational models
Sponsorship	IEEE EMB
Starting Page	44
Ending Page	50
File Size	206456
Page Count	7
File Format	PDF
ISBN	1424400325
ISSN	1557170X
DOI	10.1109/IEMBS.2006.259755
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-08-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Land mobile radio cellular systems Control system synthesis Control systems Biological systems Biological system modeling Biological control systems Cancer Medical treatment Biology computing Computational modeling
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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