NDLI: Prediction of Hemorrhagic Transformation after Acute Ischemic Stroke Using Hyperintense MCA Sign

Content Provider	IEEE Xplore Digital Library
Author	Guo, G. Wu, R.H. Zhang, Y.P. Mikulis, D.J. terBrugger, K.
Copyright Year	2006
Description	Author affiliation: Dept. of Med. Imaging, Shantou Univ. Med. Coll. (Guo, G.; Wu, R.H.; Zhang, Y.P.)
Abstract	The hyperintense appearance of the middle cerebral artery (HMCA) sign consists of a thickened MCA stem with a blurred intense signal on contrast enhanced T1-weighted magnetic resonance imaging (T1W MRI). In this article, we define it and determine its incidence, diagnostic value, and reliability by comparison with magnetic resonance angiography and digital subtraction angiography. Non-contrast CT and immediately subsequent MRI were performed on 30 consecutive patients with acute ischemic stroke within 6 hours after symptom onset. Ml patients underwent at least one follow-up MRI or non-contrast CT within 2-7 days. Initial studies were analyzed for HMCA sign on post-Gd T1WI. Vascular findings on both MRI and CT were compared with findings at MRA and DSA. Eleven patients were developed subsequent HT at follow-up studies. The HMCA sign on MRI was found in 6 hemorrhagic patients (P=0.00), and all of them had M1 occlusion on angiography. None of the patients in nonhemorrhagic group had HMCA sign on MRI. It is concluded that HMCA sign on post-Gd T1WI is highly specific and moderately sensitive indicator of acute thrombus with M1 MCA segment, as validated by angiography. Additionally, HMCA sign may be a useful marker of subsequent HT in acute ischemic stroke
Sponsorship	IEEE EMB
Starting Page	1881
Ending Page	1884
File Size	335402
Page Count	4
File Format	PDF
ISBN	1424400325
ISSN	1557170X
DOI	10.1109/IEMBS.2006.260171
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-08-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Hemorrhaging Magnetic resonance imaging Computed tomography Biomedical imaging Angiography Hospitals Medical treatment Arteries Medical diagnostic imaging Cities and towns Stroke Hemorrhagic Transformation Magnetic Resonance Imaging
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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