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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Lin, H.J. Ruiz-Correa, S. Shapiro, L.G. Speltz, M.L. Cunningham, M.L. Sze, R.W. |
| Copyright Year | 2006 |
| Description | Author affiliation: Dept. of Med. Educ. & Biomed. Informatics, Univ. of Washington (Lin, H.J.) |
| Abstract | Craniosynostosis is a serious and common pediatric disease caused by the premature fusion of sutures of the skull. Although studies have shown an increase in risk for cognitive deficits in patients with isolated craniosynostosis, the causal basis for this association is still unclear. It is hypothesized that an abnormally shaped skull produces a secondary deformation of the brain that results in the disruption of normal neuropsychological development. In this paper, we conduct a comparative analysis of our newly developed shape descriptors in an attempt to understand the impact of skull deformations on neurobehavior. In particular, we show that our scaphocephaly severity indices and symbolic shape signatures are predictive of mental ability and psychomotor functions, respectively, which suggests the possibility that secondary deformation could influence neuro-developmental status |
| Sponsorship | IEEE EMB |
| Starting Page | 3450 |
| Ending Page | 3455 |
| File Size | 501967 |
| Page Count | 6 |
| File Format | |
| ISBN | 1424400325 |
| ISSN | 1557170X |
| DOI | 10.1109/IEMBS.2006.260321 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2006-08-30 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Skull Shape Pediatrics Biomedical imaging Medical diagnostic imaging Cities and towns USA Councils Diseases Psychology Computed tomography |
| Content Type | Text |
| Resource Type | Article |
| Subject | Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition |
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