NDLI: Relative Dose Distribution In Gamma Knife Treatment Near Tissue Inhomogeneties

Content Provider	IEEE Xplore Digital Library
Author	Isbakan, F. Buyuksarac, B. Agus, O. Ulgen, Y. Bilge, H. Ozen, Z.
Copyright Year	2005
Description	Author affiliation: Inst. of Biomed. Eng., Bogazici Univ., Istanbul (Isbakan, F.; Buyuksarac, B.; Agus, O.; Ulgen, Y.)
Abstract	The primary goal in this study was to investigate 3-D dose distribution, near the areas of tissue inhomogeneities, in Gamma Knife radiosurgery with the gel dosimetry. The spherical glass balloon of a diameter of 16 cm filled with the gel forms the homogeneous phantom; and an identical balloon with two corks placed on each side to represent the air cavities forms the inhomogeneous phantom. Dose calibration is performed by irradiating vials at known doses and then utilizing the R2-dose calibration curve. Stereotactic frames and fudicial markers were attached to the phantoms for MR scanning and image processing. Dose distributions from a single shot, using all 201 Cobalt sources, delivered to a known point with identical coordinates, are calculated both in homogeneous and inhomogeneous gel phantoms. In the aspect of dosimetrical quality control, the Gamma Knife planning system predicted dose distribution is compared with the experimental results. In the homogeneous phantom, the gel dosimetry calculated dose distribution is in good agreement with the GammaPlan predicted dose distribution. However, with the inhomogeneous phantom, the dose distribution is spatially different and significant differences in dose levels are observed
Starting Page	3086
Ending Page	3089
File Size	459256
Page Count	4
File Format	PDF
ISBN	0780387414
DOI	10.1109/IEMBS.2005.1617127
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-01-17
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Imaging phantoms Dosimetry Polymer gels Calibration Oncology Glass Image processing Cobalt Head Temperature Tissue inhomogeneity Polymer gel dosimetry Stereotactic radiosurgery Gamma Knife
Content Type	Text
Resource Type	Article

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